Sensory profiles are heterogeneous in neuropathic pain disorders, and subgroups of patients respond differently to treatment. To further explore this, patients in the COMBO-DN study were prospectively assessed by the Neuropathic Pain Symptom Inventory (NPSI) at baseline, after initial 8-week therapy with either duloxetine or pregabalin, and after subsequent 8-week combination/high-dose therapy....

Standard guidelines for cancer pain treatment routinely recommend training patients to reduce barriers to pain relief, use medications appropriately, and communicate their pain-related needs. Methods are needed to reduce professional time required while achieving sustained intervention effectiveness. In a multisite, randomized controlled trial, this study tested a pain training method versus a ...

Post-traumatic trigeminal neuropathy (PTTN) is a known complication of common oral and maxillofacial procedures. The burden on the patient society often underestimated. This retrospective study included 29 patients with PTTN who underwent surgical treatment. Symptoms were differentiated, pre- postoperatively, into neuropathic discomfort loss perceptive function. Clinical patient-reported outcom...

A miniature stimulator was developed to drive a set of percutaneous wire electrodes implanted into the shoulder muscles for treating shoulder subluxation and pain in stroke survivors. The 8-channel stimulator was built around a low-power microcontroller and packaged into a pager-sized box. A single AA-size battery can power the device for about 50 hours of operation. Stimulation pulse trains wi...

OBJECTIVE We examined whether tailored activity pacing intervention was more effective at reducing pain and fatigue than general activity pacing intervention. METHOD Adults with knee or hip osteoarthritis (N = 32) stratified by age and gender were randomized to receive either tailored or general pacing intervention. Participants wore an accelerometer for 5 days that measured physical activity...

Standard assessments for fibromyalgia (FM) diagnosis and core FM symptom domains are needed for biomarker development and treatment trials. Diagnostic and symptom assessments are reviewed and recommendations are made for standards. Recommendations for existing assessments include the American College of Rheumatology FM classification criteria using the manual tender point Survey for diagnosis, ...

Abstract Background The aim of this study is to evaluate the effects successful revision operation on health quality life(QoL) and functional outcome in humeral nonunion patients. Methods This retrospective included 62 patients with from Northwest China, who were admitted Department Trauma Surgery, Honghui Hospital between March 2013 September 2019. following data retrospectively evaluated: dem...

Methods The study was a longitudinal observational, cohort study with data collected at baseline and three months. Nine integrative medicine clinics housed at academic health centers that were members of the Consortium for Academic Health Centers for Integrative Medicine (CAHCIM) were invited to participate. Each academic health center was asked to obtain IRB approval for the study. Clinic pati...

This pilot study assessed the role of Healing Touch (HT), an energy-based therapy, in modulating chronic neuropathic pain and the associated psychological distress from post spinal cord injury. Twelve veterans were assigned to either HT or guided progressive relaxation for six weekly home visits. The instruments selected showed sensitivity, although there was a large variation among the groups....

We undertook a trial on 60 patients with AO 31A2 fractures of the hip who were randomised after stabilisation of the fracture into two equal groups, one of which received post-operative treatment using a non-invasive interactive neurostimulation device and the other with a sham device. All other aspects of their rehabilitation were the same. The treatment was continued for ten days after operat...