Obesity has high prevalence rates among the Brazilian population. The aim of present study was to evaluate health resources utilization during and after surgery its economic impact on Brazil's SHS sample. Retrospective cohort using 11 carriers from Healthtech Orizon billing system, which represents 21% SHS. Patients selected were aged above 18 years with severe obesity inferred through bariatri...

Total RNA extracted from a rat liver cell line (BRL 3A) that synthesizes rat insulin-like growth factor II (IGF-II) was translated in a reticulocyte lysate cell-free system. Incubation of the translation products with antisera to mature rat IGF-II (Mr 8700) selectively immunoprecipitated a Mr 21,600 protein. We propose that this protein represents pre-pro-IGF-II.

The in vitro inactivation of gentamicin by carbenicillin and a new semisynthetic penicillin, ticarcillin (BRL 2288), has been demonstrated. Gentamicin half-lives have been studied in eight patients with end-stage renal failure, and a 25 to 74% reduction in half-life has resulted from the concomitant administration of therapeutic doses of carbenicillin and ticarcillin.

The cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl- channel that is regulated by cAMP-dependent phosphorylation and by intracellular ATP. Intracellular ATP also regulates a class of K+ channels that have a distinct pharmacology: they are inhibited by sulfonylureas and activated by a novel class of drugs called K+ channel openers. In search of modulators of CFTR Cl- channels,...

Stress can trigger the relapse of drug use in recovering cocaine addicts and reinstatement in rodent models through mechanisms that may involve norepinephrine release and β-adrenergic receptor activation. The present study examined the role of β-adrenergic receptor subtypes in the stressor-induced reinstatement of extinguished cocaine-induced (15 mg/kg i.p.) conditioned place preference in mice...

A new pump-seeded, short-cavity Brillouin ring laser source layout intended for sensing applications is showcased, showing increased high maximum output (1.5 mW), a strong linewidth narrowing effect (producing light with of 10 kHz) and limited relative intensity noise (RIN ~ −145 dB/Hz), providing an ultranarrow, highly stable BRL that can also be employed as pump-probe optical time-domain anal...

Background: The objective of this work was to decontaminate synthetic sewage from fouracid blue (BRL) dye, with characteristics similar those the textile industry, determine correlation between flow rate, permeability and removal hexavalent chromium (Cr+ 6), Cupper (Cu), chemical oxygen demand COD color using Paradise Muse filter bed. Methods...

stability to /Mactamases (evinced by lower MICs against /Mactamase producing strains of Haemophilus and Staphylococcus) compared to 1. However, 2 was produced as a mixture of stereoisomers which were not easily separated and was therefore not promising for further study. Following the theme of 2-substitution, we subsequently discovered a series of bicyclic acrylic penicillins3) of which the mos...