نتایج جستجو برای: bromocriptine
تعداد نتایج: 1198 فیلتر نتایج به سال:
The dopaminergic drug bromocriptine inhibited the release of insulin from isolated mouse pancreatic islets. The effect was counteracted by haloperidol or pimozide. It is suggested that insulin release may be inhibited through activation of D-2 dopaminergic receptors in the pancreatic beta-cells.
Diabetes mellitus (DM), one of the oldest diseases known to mankind has always been difficult treat even with availability a variety medications. In such scenario, Food and Drug Administration (FDA) approved novel therapeutic, bromocriptine, different mechanism action than traditional medications since 2009 but not used as either first-line therapy or add-on therapy. this systematic review, we ...
Background and Purpose Dopamine agonists targeting D2 receptor have been used for decades in treating pituitary adenomas. There has little clear evidence implicating the canonical G protein signalling as mechanism by which suppresses growth of tumours. We hypothesize that ?-arrestin2-dependent is molecular dictating inhibitory effects on tumour growth. Experimental Approach The involvement ?-ar...
The negative symptoms of schizophrenia still cause one of the major problems in therapeutic work with schizophrenics. Although there has been great progress in the field of pharmacology for identifying effective drugs to alleviate the negative symptoms. We are still far away from having satisfactory and successful results. The purpose of the present project is to study the effects of a type of...
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