Autopsy findings suggest that lung surfactant is damaged in the adult respiratory distress syndrome. In the present study 225 bronchoalveolar lavage specimens (78 from 36 patients, 1-78 yr old with respiratory failure, 135 from another 128 patients with other respiratory disease, and 12 from healthy controls) were assayed for the lung profile [lecithin/sphingomyelin (L/S) ratio, saturated lecit...

A correlation study of the cultured bacteria from paired sputum and bronchoalveolar lavage fluid samples was performed. The rates of concordant culture-positive paired specimens that were isolated within 1 or 7 days were 93.7% and 96.5%, respectively, suggesting that the culture of readily collectable sputum specimens may result in useful microbiologic diagnosis.

Four cases of polyarthritis concomitant with active tuberculosis is reported. In three patients pulmonary tuberculosis was confirmed by identification of Mycobacterium tuberculosis in the sputum and bronchoalveolar lavage specimens, and in another one tuberculous lymphadenitis was confirmed by excisional biopsy. In all patients arthritis resolved by tuberculosis treatment and did not recur ...

The beneficial effect of short-term smoking reduction in reducing lower respiratory tract inflammation was assessed in 15 healthy heavy smokers. All underwent fibreoptic bronchoscopy and bronchoalveolar lavage and were then treated with at least 20 mg of nicotine gum daily. Self-reported cigarette consumption decreased from 50.7 +/- 2.3 to 18.8 +/- 1.5 (p less than 0.001) cigarettes daily, and ...

Titanium dioxide nanofibres (TiO2) were intratracheally instilled in dose of 4 mg/0.2 mL saline solution per animal (Wistar rats). After 48 hours and 14 days the animals were exsanguinated (under i.p. thiopental narcosis), bronchoalveolar lavage (BAL) was perfomed and cells from BAL fluid were isolated. Following inflammatory, cytotoxic and oxidative stress BAL parameters were examined: differe...

A 63-year-old man presented with recurrent episodes of acute wheezy bronchitis accompanied by fever (39 5°C). His illness had started three months before admission. After treatment with intramuscular ampicillin (1 g three times daily) fever subsided but he continued to cough and wheeze. Because of these symptoms the patient was sent for further examination. History revealed a subtotal gastrecto...

Researchers over the past 40 years have utilized bronchoalveolar lavage (BAL) as a tool to help expand our knowledge of pulmonary medicine. Many reports have documented BAL as a safe procedure for research subjects. New technologies, such as flow cytometry, have provided much needed insight into the mechanisms behind several pulmonary diseases. The concept of the lung as an easily accessible mu...

Background-Recently, we showed that it is possible to distinguish between three common interstitial lung diseases (ILD) with similarities in clinical presentation by using a number of selected variables derived from bronchoalveolar lavage fluid (BALF) analysis. The aim of this study was to develop a more general discriminant model, based on polychotomous logistic regression analysis. Study desi...

involvement; neither survived a year and both required thoracotomy to establish the diagnosis. In summary, the study by Cordier and colleagues includes all presentations of pulmonary amyloidosis and provides sufficient clinical detail for a practicing physician to classify properly and thereby permit optimal management of patients presenting with this uncommon manifestation of a disease whose p...

from january 1982 to april 1987 , 1500 cases of fiberoptic bronchoscopy (fob) were performed. among these cases, 37 were suspected of having pulmonary tuberculosis but their sputum examination was either negative or they were not able to expectorate. in all these cases pulmonary tb was confirmed either by bronchoalveolar lavage (bal) fluid examination or by biopsy. we conclude that fob is a val...