We describe the clinical and biological features of ten patients with a survival superior to ten years (long survival), out of 175 patients diagnosed with Adult T-cell Leukemia/Lymphoma (ATL) in Martinique (1983-2013). There were 5 lymphoma and 5 chronic subtypes. Five of them (3 chronic, 2 lymphoma) had been treated with valproic acid (VA) for neurological disorders developed before or after A...

In this work, fresh soybean meal was used as the substrate for both batch and continuous experiments in a rotational drum fermentation (RDF) system to characterize the acidogenic process of solid organic waste degradation at high unionized volatile acid (U-VA) level and evaluate the effect of water flushing on the acidogenic performance. The experiments were conducted under mesophilic condition...

One of the most widely employed histone deacetylases inhibitors in the clinic is the valproic acid (VA), proving to have a good tolerance and low side effects on human health. VA induces changes in chromatin structure making DNA more susceptible to damage induction and influence DNA repair efficiency. VA is also proposed as a radiosensitizing agent. To know if VA is suitable to sensitize human ...

BACKGROUND AND PURPOSE The vertebral artery (VA) is important for the development of the transverse foramen (TF). Most studies of these structures have focused on anatomical anomalies. Therefore, we investigated quantitatively the association between the relative sizes of the TF and VA. METHODS We recruited a consecutive series of subjects who underwent CT angiography to estimate the relative...

A higher frequency of hypoplastic vertebral artery (VA) in patients with migraine with aura than in normal controls has been documented. However, the role of a hypoplastic VA in a migraine attack remains unclear. The aim of our work was to measure the net VA flow volume and related spectral parameters in patients with migraine with aura and a hypoplastic VA. From January 2005 to October 2005 we...

We show that human adenovirus inhibits RNA interference (RNAi) at late times of infection by suppressing the activity of two key enzyme systems involved, Dicer and RNA-induced silencing complex (RISC). To define the mechanisms by which adenovirus blocks RNAi, we used a panel of mutant adenoviruses defective in virus-associated (VA) RNA expression. The results show that the virus-associated RNAs...

OBJECTIVE To examine past comparisons of the costs of the Veterans Health Administration (VA) and of non-VA providers to determine lessons and data requirements for future cost comparisons, particularly those assessing VA efficiency and to determine whether VA should purchase care from non-VA providers. CONCEPTUAL FRAMEWORK Over the past two decades, researchers have tried to establish how VA...

INTRODUCTUION Symptomatic severe vertebral artery (VA) stenosis may be treated safely with stent supported angioplasty via femoral access. There is limited clinical data on transradial approach for VA angioplasty in case of peripheral artery disease. AIM To evaluate the safety and efficacy of transradial angioplasty of symptomatic VA stenosis. MATERIAL AND METHODS Fifteen patients (age 66 ±...

The distance d(va,vb) between two vertices of a simple connected graph G is the length shortest path va and vb. Vertices va,vb are considered to be resolved by vertex v if d(va,v)≠d(vb,v). An ordered set W={v1,v2,v3,…,vs}⊆V(G) said resolving for G, any va,vb∈V(G),∃vi∈W∋d(va,vi)≠d(vb,vi). representation with respect W denoted r(v|W) an s-vector(s-tuple) (d(v,v1),d(v,v2),d(v,v3),…,d(v,vs)). Using...

There are few reports describing stroke due to the acute occlusion of the vertebral artery (VA) origin successfully treated by endovascularily. The authors report a case of 78-year-old man suffering from stroke owing to acute VA origin occlusion associated with contralateral hypoplastic VA leading to basilar artery (BA) thrombosis. Cerebral angiography demonstrated that the right VA was occlude...