Esophageal cancer is the eighth most common cancer and causes the sixth highest cancer-related mortality worldwide. The 5-year survival of patients suffering from esophageal cancer in either advanced stage or metastasis is less than 20%. MicroRNAs are small, well conserved, non-coding RNA molecules that either repress translation or promote mRNA degradation based on the degree of complementary ...

background only a few studies in western countrieshave investigated the association between gastroesophageal reflux disease(gerd) and mortality at the general population level and they have shown mixedresults. this study investigated the association between gerd symptoms andoverall and cause-specific mortality in a large prospective population-based studyin golestan province, iran. methods base...

To estimate the cancer incidences and mortalities in China in 2010, the National Central Cancer Registry (NCCR) of China evaluated data for the year of 2010 from 145 qualified cancer registries covering 158,403,248 people (92,433,739 in urban areas and 65,969,509 in rural areas). The estimates of new cancer cases and cancer deaths were 3,093,039 and 1,956,622 in 2010, respectively. The percenta...

introduction primary malignant esophageal melanoma makes up 0.1% to 0.2% of all esophageal malignancies. most physicians assume malignant melanoma as a skin originated neoplasm, however this type of melanoma can occur anywhere in the gastrointestinal tract especially in the esophagus. thus, it is essential to consider malignant melanoma in differential diagnosis of any esophagus masses. case pr...

iran has had incremental incidence of traffic accident mortality since introduction of mechanization about a century ago. but the newest data from iran show decrease in the absolute number of deaths, death per 10,000 vehicles and death per 100, 000 populations. despite its huge impact on health and economy, research in the field of traffic crashes is still scant and there are still deficiencies...

recancerous condition in which the risk of cancer has been overestimated lication bias (with positive findings being accepted more easily than dings). A reasonable estimate is 0.5 cancers occurring per 100 patientrisk is estimated for males of Caucasian descent. In addition, individual ferring a higher risk are smoking and a long history of reflux symptoms. At enocarcinoma in the esophagus is l...

This study divided patients with esophageal cancer and multiple primary cancers into two groups, a head and neck cancer (HNC) group and a non-head and neck cancer (NHNC) group. These groups were then evaluated on the basis of clinical and pathological studies. Among 92 patients with esophageal cancer as one of multiple primary cancers, 38 (41.8%) were assigned to the HNC group. The following ch...

Esophageal carcinoma is the eighth most common cancer, and the sixth most common cause of cancer-related deaths worldwide [1]. Esophageal carcinomas in developing nations account for more than 80% of the total cases and deaths [1]. Esophageal cancer can arise as esophageal squamous cell carcinoma (ESCC) or esophageal adenocarcinoma (EAC), which have distinct etiological and pathological charact...

PURPOSE To establish effective antitumor immunotherapy for esophageal cancer, we tried to identify an useful target antigen of esophageal cancer. EXPERIMENTAL DESIGN We did cDNA microarray analysis to find a novel candidate antigen, proliferation potential-related protein (PP-RP). We examined cytotoxicity against tumor cells in vitro and in vivo of CTLs specific to PP-RP established from esop...