BACKGROUND Hypertension (HT) is a common complication of anti-angiogenic therapy. Its incidence, treatment and complications are undefined. PATIENTS AND METHODS Retrospective review of patients treated with bevacizumab (BV) from 2003-5. Common toxicity criteria (CTC) for adverse events version 3.0 were used. RESULTS Fifty-five out of the 154 patients treated with BV (35%) experienced HT. El...

This study was conducted as part of a double-blind randomised placebo-controlled trial, the aim of which was to determine whether vitamin C could reduce the recurrence risk of pre-term labour. In this study, women with a history of pre-term labour in a preceding pregnancy were randomised to receive either 250 mg vitamin C or a matching placebo twice daily until 34 weeks' gestation. They attende...

To perform a fast and reproducible analysis in bone histomorphometry, we developed an automatic method for calculating static and dynamic parameters. A color automatic image analyzer (SAMBA 200) was used to obtain the usual parameters of bone histomorphometry: bone volume (Cn-BV%TV), osteoid volume (Cn-OV%BV), and osteoid surface (Cn-OS%BS). A specialized algorithm was designed for calculation ...

The purpose of this work is to investigate the stability property of some models which are currently used in image processing. Following L. Rudin, S.J. Osher and E. Fatemi, we decompose an image f ∈ L2(R2) as a sum u+ v where u belongs to BV(R2) and v belongs to L2(R2). The Banach space BV is aimed at modeling the objects contained in the given image. the optimal decomposition minimizes the ene...

We studied the total vascular pressure-volume relationship and cardiac output (CO) in conscious rats receiving DOCA-salt or sham treatment. The mean circulatory filling pressure (MCFP) was measured by briefly inflation an indwelling balloon in the right atrium, and the MCFP-blood volume (BV) relationship over +/- 10% of BV was determined by rapid blood infusion or withdrawal. CO was measured in...

This paper studies the space of BV 2 planar curves endowed with the BV 2 Finsler metric over its tangent space of displacement vector fields. Such a space is of interest for applications in image processing and computer vision because it enables piecewise regular curves that undergo piecewise regular deformations, such as articulations. The main contribution of this paper is the proof of the ex...

In order to screen a suitable resin for the preparative simultaneous separation and purification of syringin, eleutheroside E and isofraxidin from Acanthopanax senticosus, the adsorption and desorption properties of 17 widely used commercial macroporous resins were evaluated. According to our results, HPD100C, which adsorbs by the molecular tiers model, was the best macroporous resin, offering ...

STP-BV is a bounding volume made of patches of spheres and toruses. These patches are assembled so that a convex polyhedral hull is bulged, in a tunable way, into a strictly convex form. Strict convexity ensures at least C property of the distance function –and hence, its gradient continuity. STPBV were introduced in our previous work [1], but proximity distance queries were limited to pairs of...

This study tests the hypothesis that conscious rabbits late in pregnancy (P), but not at midgestation (MP), are less able to maintain arterial pressure during hemorrhage. Blood volume (BV) was elevated ( P < 0.05) by an average of 13 ± 4 (MP) and 35 ± 3% (P). Rabbits were bled in both the nonpregnant (NP) and P state at 2% of the initial BV per minute. The hemorrhage was stopped after arterial ...

Microglia activation and the release of various inflammatory cytokines are largely related to neurological diseases, including Parkinson's, Alzheimer's, and other brain diseases. The suppression of microglial cells using natural bioactive compounds has become increasingly important for brain therapy owing to the expected beneficial effect of lower toxicity. Scoparone (6,7-dimethoxycoumarin), a ...