BACKGROUND The activating mutations of micro RNA (miR)-17 have been revealed in tumors such as human non-Hodgkin's lymphoma and T cell leukemia. However, it is unclear about the role of miR-17 in glioma cells. The current study aimed to investigate effects of miR-17 mimics or inhibitor on the viability and migration of rat glioma C6 cells, and explore possible mechanisms. METHODS The expressi...

A method for determination of atomic lifetimes from the value of dispersion coefficient C6 of molecular potentials correlating to two ground-state atoms is proposed. The method is illustrated with atomic Cs using C6 deduced from high-resolution Feshbach spectroscopy. The following lifetimes are determined: t6P1/2534.80 60.07 ns and t6P3/2530.3960.06 ns. The underlying electric-dipole matrix ele...

An 8-year-old Warmblood gelding presented with a history of progressive ataxia for 6 weeks. Intra- and intervertebral ratios measured from lateral radiographs the cervical spine were within normal limits. Computed tomographic myelography revealed focal compression dorsal ventral contrast column as well displacement spinal cord canal due to bulging soft tissue attenuating material in half juncti...

Per- and polyfluoroalkyl substances (PFAS) are a common contaminant in municipal landfill leachate recognized as pollutant on global scale. The present work examined foam fractionation (FF) batch continuous modes an appropriate treatment technique for PFAS removal the found stable efficiency of greater than 90% PFOA (C7), PFOS (C8), PFHxS (C6), PFHpA (C6) 6:2 FTSA (C6). For other such PFNA PFPe...

RS21-C6, which is highly expressed in all vertebrate genomes and green plants, is proposed to have nucleoside triphosphate pyrophosphohydrolase activity. Here, we report the crystal structures of the core fragment of RS21-C6, named RSCUT, and the complex with the substrate 5-methyl dCTP. The refined structure of RSCUT consists mainly of alpha-helices and shows formation of a tightly associated ...

The monoclonal antibody (McAb) designated as C6 against erythrocytic stage of Plasmodium falciparum Fcc7801/HN showed significant growth inhibition of P. falciparum in vitro, having cross immunofluorescence reaction with P. falciparum Fcc-1/HN, Fcc7802/HN, Fcc8703/JS and P. berghei, P. cynomolgi. McAb C6 bound to the antigen distributed evenly over the entire surface of merozoites of P. falcipa...

Abstract The synthesis of Lipoxin B 4 analogs (LXB ) to gain access stabilized inflammation resolving compounds is an actual field research. Focusing on variation and stabilization the conjugated E,Z,E,E C6–C13 tetraene moiety natural LXB , a methylene bridge introduced between C6 C11 suppresses any Z/E isomerization C8–C9 olefin. Intending enable prospective structure variations in connection ...

OBJECTIVE To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. METHODS C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the concentration of 1 μg/ml in the culture medium, and then cell viability was evaluated. RESULTS Pho...

Flavonoids are a group of low molecular weight polyphenolic compounds derived from plants. 5,7-dihydroxy-8methoxy ̄avone (Wogonin), a ̄avonoid originated from the root of Scutellaria baicalensis Georgi, has been shown to exert various anti-in ̄ammatory effects such as inhibition of nitric oxide (NO) and prostaglandin E2 production in macrophages. Because glial cells have been previously shown to ...