Objetivo: Analisar as características da Psoríase. Revisão bibliográfica: A psoríase é uma doença sistêmica crônica imunomediada que afeta aproximadamente 100 milhões de pessoas em todo o mundo. parece ser resultado interação desregulada entre células imunes, queratinócitos pele e ambiente, levando a um processo inflamatório persistente modulado por T ativadas citocinas pró-inflamatórias. está ...

Introduction: Vitiligo is a specific, common, often heritable acquired disorder characterized by well-circumscribed milky white cutaneous macules and patches devoid of identifiable melanocyte. Treatment vitiligo, though quite frustrating, includes repigmentation therapies like Topical glucocorticoids, calcipotrieinene, PUVA (Psoralen + Ultraviolet Light A). The combination calcipotriol proves e...

Atopic dermatitis is a chronic relapsing inflammatory common skin disease. It has complex pathophysiology, that involves strong genetic predisposition, epidermal dysfunction, and type 2 inflammation. Kaempferol natural flavonoid widely found in tea, vegetables, fruits. wide range of beneficial pharmacological activities, including excellent anti-oxidation anti-inflammation. However, the therape...

Cholangiopathies are chronic liver diseases in which damaged cholangiocytes trigger a proinflammatory and profibrotic reaction. The nuclear vitamin D receptor (VDR) is highly expressed exerts immune-regulatory functions these cells. In the present study, we examined protective function of VDR other signaling pathways cholangiopathy cholangiocytes. Vdr was invalidated Abcb4 knockout mice, widely...