INTRODUCTION Calcium hydroxide has been extensively used as the gold standard for direct pulp capping in clinical dentistry. It induces proliferation, migration, and mineralization in dental pulp stem cells (DPSCs), but the underlying mechanisms are still unclear. The aim of this study was to investigate the role of the mitogen-activated protein (MAP) kinase pathway in calcium hydroxide-induced...

OBJECTIVE Up to 90% of the flora of an infected root canal consists of obligate anaerobic bacteria. However, most studies have centred on microaerophiles. This quantitative assay investigated the antibacterial effects against Fusobacterium nucleatum and Parvimonas micra of gutta-percha (GP) points containing either calcium hydroxide (Ca(OH)(2)) or chlorhexidine (CHX) compared to those of conven...

Purpose. To evaluate the mineral ion loss of root dentine after treatment with 2% chlorhexidine solution (CHX) and to compare its yield and flexural strength (fs) after exposure to calcium hydroxide [Ca(OH)2]. Materials and Methods. Dentine bars (DB) were made from 90 roots of bovine incisors and randomized into three groups: GControl: distilled/deionized water (DDW), GNaOCl: 2.5% sodium hypoch...

AIM To compare the efficiency of removing calcium hydroxide [Ca(OH)(2)]/chlorhexidine (CHX) (gel), Ca(OH)(2)/CHX (solution) and Ca(OH)(2)/saline pastes with the use of instrumentation and irrigation with sodium hypochlorite and ethylene diamine tetraacetic acid (EDTA) solutions. Moreover the role of the patency file in the cleanliness of the apical third of the root canal was evaluated. METHO...

The access ionization attempt may occur during the coronary period, which lead to a posterior dental access. maintenance of primary tooth is important, especially in cases permanent agenesis. aim this study report clinical case about perforation sealing, endodontic retreatment, and installation fixed prosthesis lower molar. A patient was selected from clinic Fapac/Itpac Porto Nacional - TO, asy...

The objective of this research was to determine if gutta-percha points with calcium hydroxide [Ca(OH)2] improve the apical seal after root canal filling and if the master point does it alone. Human single recently extracted teeth were biomechanically prepared and the root canals filled by the lateral condensation technique with ZOE and gutta-percha points, with or without calcium hydroxide. The...

Introduction: The ultimate goal of endodontic treatment is to eliminate the bacterial infection in the root canal system. While mechanical debridement combined with chemical irrigation removes the bulk of microorganisms, residual bacteria are readily detectable in approximately one-half of teeth just prior to obturation. Laser light can be used to destroy bacteria. This in vitro study was perfo...

INTRODUCTION The aim of this in vitro study was to compare the effectiveness of three intracanal medicaments in disinfecting the root canal and dentin of experimentally infected human teeth with Enterococcus faecalis (EF). MATERIALS AND METHODS One hundred extracted human single-rooted teeth were used. After root canal preparation, teeth were mounted in epoxy resin. Following sterilization, t...

This study explores the delivery of novel calcium hydroxide [Ca(OH)₂] microparticles loaded with chlorhexidine (CHX) for potential dental therapeutic and preventive applications. Herein, we introduce a new approach for drug-delivery to deep dentin-surfaces in the form of drug-loaded microparticles. Unloaded Ca(OH)₂ [Ca(OH)₂/Blank] and CHX-loaded/Ca(OH)₂ microparticles were fabricated by aqueous...