Obesity has become a worldwide epidemic and is associated with significant morbidity and mortality. More than two-thirds of adults in the United States are either trying to lose weight or prevent weight gain. Very low calorie diets, diets with energy levels between 200 and 800 kcal/day, are used commonly for rapid weight loss. These diets are generally safe and well-tolerated and have been repo...

Childhood obesity is becoming more prevalent; however, the influence of obesity or dieting during childhood on outcomes in adulthood is poorly understood. The aim of this study was to examine the effects of short-term calorie restriction (CR) and high-calorie feeding with high-fat or high-sucrose diets during early life on the development of glucose tolerance and diabetic nephropathy in later l...

Calorie restriction extends life-span in a wide variety of organisms. Although it has been suggested that calorie restriction may work by reducing the levels of reactive oxygen species produced during respiration, the mechanism by which this regimen slows aging is uncertain. Here, we mimicked calorie restriction in yeast by physiological or genetic means and showed a substantial extension in li...

Severe overfeeding of critically ill patients results in increased complications without clinical benefits. However, the optimal timing and amount of nutrition to feed critically ill adults has not been established. There are multiple prediction equations for estimating calorie expenditure of critically ill patients, but most studies comparing the accuracy of different prediction equations are ...

Calorie restriction is known to extend lifespan among organisms by a debating mechanism underlying nitric oxide-driven mitochondrial biogenesis. We report here that nitric oxide generators including artemisinin, sodium nitroprusside, and L-arginine mimics calorie restriction and resembles hydrogen peroxide to initiate the nitric oxide signaling cascades and elicit the global antioxidative respo...

Calorie Restriction (CR) is a defined intervention tool currently being studied as an effort to achieve numerous health benefits and increase longevity. Currently, there is a large body of research that indicates a multitude of health benefits and positive associations; however, there is also a plethora of opposing research. Through investigation of epigenetics, the efficacy of calorie restrict...

The present study investigated the effect of taxing high-energy dense products and subsidizing low-energy dense products on changes in calorie consumption. More specifically, we hypothesized that 'more impulsive' individuals were less influenced by such pricing strategies compared to 'less impulsive' individuals. Contrary to our hypothesis, results showed that 'more impulsive' individuals adjus...

BACKGROUND Although data from longitudinal studies are sparse, effort-reward imbalance (ERI) seems to affect work ability. However, the potential pathway from restricted work ability to ERI must also be considered. Therefore, the aim of our study was to analyse cross-sectional and longitudinal associations between ERI and work ability and vice versa. METHODS Data come from the Second German S...

Objective: This study aimed to analyze the effect of a combination calorie restriction and moderateintensity continuous exercise on FFA levels visceral fat weight in female mice exposed high-caloriediet.Material Method: research was randomized posttest used only control group design with femalemice as sampl Balb/c (Mus musculus), 8 weeks old, 20-30 grams. It randomly divided into fourgroups, na...