Antonio Marcondes Lerario, Luciana Pinto Brito, Beatriz Marinho Mariani, Maria Candida B V Fragoso, Marcel Autran Cesar Machado, Roberto Teixeira I Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular (LIM-42), Disciplina de Endocrinologia, Hospital das Clı́nicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. II Laboratório de Inv...

According to World Health Organization, antibiotic resistance is rising dangerously high levels in all parts of the world. New mechanisms are emerging and spreading globally, threatening our ability treat common infectious diseases. Therefore, searching for new antimicrobial agents natural origin an extraordinary global problem. The work aimed determine activity lyophilized enzymatic lysate cel...

KOH: potassium hydroxide INTRODUCTION Aspergillus sp, Candida sp, and zygomycoses can disseminate rapidly in an immunocompromised host, causing significant morbidity and mortality. Serum testing, tissue biopsy, and culture are used to confirm a suspected diagnosis, but waiting for results may delay initiation of life-saving treatment. We report a case of disseminated aspergillosis presenting wi...

Plant extract exhibited unique therapeutic characteristics due to their high content of chemical formulas with multiple medical effects. The plant extracts have shown a great advancement in controlling cardiovascular and metabolic disorders, as well as, it was used antibacterial, antifungal, anti-cancer, anti-inflammatory agents. Cinnamomum has been herbs from ancient times along its uses spice...

Estrogen deficiency around menopause can cause growth of abnormal flora leading to infections. The aim of the study was to assess the prevalence of bacterial vaginal infections among the asymptomatic pre and postmenopausal women. High vaginal swab samples were collected and the microorganisms were identified. Their antibiotic susceptibility pattern was noted. Escherichia coli, Staphylococcus au...

We reported herein the synthesis, antifungal activity, docking and in silico ADME prediction studies of four novel series of sulfones 6a-f, 8a-c, 10a-f and 12a-c. All the newly synthesized sulfones were tested against four strains of Candida (including fluconazole-resistant Candida), two strains of Aspergillus, two dermatophytic fungi (Trichophytons mentagrophyte and Microsporum canis) and Sync...

A long lasting, protective and film forming HPCH-based medical device was developed and tested in a novel in vitro human nail infection model. HPCH-treated and untreated human distal fingernail fragments were disposed on the culture surface of Trychophyton rubrum, T. mentagrophytes, Scopulariopsis brevicaulis or Candida parapsilosis. After incubation for one or three weeks, the fragments were c...

cheese 13 RUNNING TITLE: Candida cabralensis sp. nov. from Cabrales cheese 14 15 Abstract 24 Three yeast strains, 1AD8, 3AD15 and 3AD23, belonging to a previously unknown 25 yeast species were isolated from two independent batches of the Spanish blue-veined 26 Cabrales cheese, a traditional cheese manufactured without the addition of starter and 27 mould cultures. Physiological characterisation...