background: testis tissue xenografting and the resultant sperm in a xenograft may provide a unique approach to rescue the genetic material of males that die prematurely and is a model for the study of human spermatogenesis and can represent an alternative approach for fertility preservation in cancer patients. this study was aimed to evaluate the xenogenic dog sperm in formation of male pronucl...

background and aims. the aim of this study was to determine whether variations in the mesiodistal dimensions of mandibular canines had any role in sex determination. materials and methods. the study comprised of patients in the 19‒24-year age group (20 males and 20 females). mesiodistal dimensions of mandibular canines was measured at the maximum mesiodistal width, first intraorally, then on pl...

background: visceral leishmaniasis (vl) is caused by leishmania infantum in mediterranean basin and is an endemic disease in some parts of iran. canines are the main reservoirs of vl in most of the endemic areas. different serological methods have been introduced for diagnosis of canine visceral leishmaniasis (cvl). objective: in this survey a fucose-mannose ligand (fml) elisa, using native l. ...

background: canine distemper (cd) is a lethal systemicdisease affecting a wide variety of terrestrial carnivores.objectives: this study was performed to survey epidemiologicaland molecular characteristics of the canine distemper virus(cdv) strains circulating in iran. methods: in this study, 19cdv-suspected unvaccinated dogs from northeast and center ofiran were analyzed for presence of cdv nuc...

Primary cutaneous lymphomas (PCLs) are the second most common group of extranodal non-Hodgkin lymphomas (NHL) with an estimated annual incidence of 1/100.000. Interferons (IFNs) are used in mono or combination therapy for cutaneous lymphomas especially for cutaneous T-cell lymphomas (CTCL) for years. IFN-α is the most widely-used type for cutaneous lymphomas. IFN-α has been shown to be a highly...

background: low-intensity laser therapy (lilt) can be utilized for different treatments in the fi eld of orthodontics and dentofacial orthopedics. the aim of the present study was to evaluate the effi cacy of lilt on (1) the rate of canine movement during canine retraction phase and (2) evaluate the radiographic changes occurring during lilt around the irradiated area. materials and methods: a ...

We analyzed the susceptibility of 10 AKXD recombinant inbred (RI) mouse strains to lymphomas. These strains were derived from crosses of AKR/J, a highly lymphomatous strain, and DBA/2J, a weakly lymphomatous strain. Of the 10 strains analyzed, nine showed a high incidence of lymphoma development. As with the other 13 AKXD strains analyzed previously (M. L. Mucenski, B. A. Taylor, N. A. Jenkins,...

Aim: Abnormal expression patterns of beta-tubulin isotypes may provide a molecular rationale for the behaviour of lymphoma subtypes. In the present study class II and III beta-tubulin expression was assessed in non-neoplastic and neoplastic lymphoid tissues with reference to potential utility as new tumour biomarkers. Methods and results: In this cross-sectional study class II and III beta-tubu...

Comparative oncology is a developing research discipline that is being used to assist our understanding of human neoplastic diseases. Companion canines are a preferred animal oncology model due to spontaneous tumor development and similarity to human disease at the pathophysiological level. We use a paired RNA sequencing (RNA-Seq)/microarray analysis of a set of four normal canine lymph nodes a...

Anaplastic large cell lymphomas (ALCLs) are a group of CD30 positive T-cell non-Hodgkin lymphomas, accounting for only 3% all lymphomas. As per the 2017 World Health Organization updated classification, there four variants ALCL: anaplastic lymphoma kinase (ALK) positive, ALK negative, primary cutaneous, and breast-implant associated. The different ALCL share overlapping clinical presentations p...