CAPE Internet Talk was started as part of CAPE follow-up activities to continue ties with CAPE alumni and those who are interested in professional development in English teaching. It is hoped that this would increase our bond and aloha among former participants, and that the information in the TALK would help our alumni and friends/members review what they know and deepen their understanding of...

Caffeic acid phenethyl ester (CAPE), a natural polyphenolic compound with many biological activities, has been shown to be protective against ischemia-reperfusion injury. We have synthesized six new catechol ring-fluorinated CAPE derivatives and evaluated their cytotoxic and cytoprotective effects against menadione-induced cytotoxicity in human umbilical vein endothelial cells. These results pr...

Propolis is a mixture produced by honeybee, which have hundreds of polyphenols. Caffeic acid phenethyl ester (CAPE) [Figure 1], an active component of honeybee propolis has been determined to have antioxidant, anti-inflammatory, antiviral, and anticancer activities [1,2]. It has been used to prevent oxidative stress-based deterioration in cells/tissues/organs in both cell culture and experiment...

Division of Pharmacology, Faculty of Medicine and Health Sciences, University of Stellenbosch, Cape Town, South Africa (P.S.F., B.R.) Division of Drug Metabolism and Pharmacokinetics, Novartis Institute of Biomedical Research, Basel, Switzerland (H.G., H.S., A.J.) Synexa Life Sciences, Montague Gardens, Cape Town, South Africa (P.J.D.) Division of Medical Microbiology, Faculty of Medicine and H...

Richard N van Zyl-Smit, Anke Binder, Richard Meldau, Patricia L Semple, Alicia Evans, Peter Smith, Eric D Bateman, Keertan Dheda Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, South Africa. Division of Pharmacology, Department of Medicine, University of Cape Town, South Africa. Department of Infection, University ...

We read with great interest the article by İlhan et al. (1) entitled “The effect of caffeic acid phenethyl ester on isoproterenol-induced myocardial injury in hypertensive rats published in Anatol J Cardiol 2014; 14: 576-82.”. It is a well-designed and well-written manuscript and is original. This work aimed to evaluate the potential of caffeic acid phenethyl ester (CAPE) to prevent damage afte...

A recent paper by Erdemli et al. on this journal reviewed the antiviral properties of caffeic acid phenetyl ester (CAPE) [1]. Recent literature showed that CAPE has also anti-inflammatory and immune-modulatory effects, as like as many other plant-derived phenolics [2] but its ability to exert an anti-inflammatory role has never been assessed in clinical trials, therefore, its activity on humans...

In the summer of 1996, southeastern North Carolina, United States, was struck by two hurricanes, with the second (Hurricane Fran) doing considerably more damage than the first (Hurricane Bertha). The Cape Fear watershed, largest in North Carolina, suffered from severe water quality problems for weeks following Fran, including a massive fish kill in the Northeast Cape Fear River. Post-hurricane ...

The Cape Verde kite (Milvus milvus fasciicauda) is considered to be one of the rarest birds of prey in the world and at significant risk of extinction. For this reason there is great interest in both the taxonomic and the population status of this group. To help resolve its taxonomic status, we provide phylogenetic analyses based on three mitochondrial genes for a sampling of kites in the genus...

Head and neck cancers, which affect 650,000 people and cause 350,000 deaths per year, is the sixth leading cancer by cancer incidence and eighth by cancer-related death worldwide. Oral cancer is the most common type of head and neck cancer. More than 90% of oral cancers are oral and oropharyngeal squamous cell carcinoma (OSCC). The overall five-year survival rate of OSCC patients is approximate...