Lily, R. E. C., Cole, P. V., and Hawkins, L. H. (1972). Brit. J. industr. Med., 29, 454-457. Spectrophotometric measurement of carboxyhaemoglobin. An evaluation of the method of Commins and Lawther. The spectrophotometric method of Conmmins and Lawther for the measurement ofcarboxyhaemoglobin (COHb) concentration was evaluated for both accuracy and sensitivity. The method was calibrated by equi...

An 11-week crossover study was carried out in which 12 subjects smoked high-nicotine (1.84 mg standard yield) and low-nicotine (0.6 mg) cigarettes after an initial period of smoking their usual brands with a medium-nicotine yield (mean 1.4 mg). Plasma and urine nicotine concentrations, carboxyhaemoglobin (COHb) concentration, puffing behaviour, 24-hour cigarette consumption, and butt nicotine c...

Carboxyhaemoglobin measured in 50 infant deaths showed no significant difference between home and hospital deaths nor between explained and unexplained deaths. Carbon monoxide toxicity is unlikely to have an important role in the pathogenesis of sudden infant deaths. The generally low carboxyhaemoglobin concentrations are probably due to endogenous production.

Porphyrin molecules have a highly conjugated cyclic structure and are theorized to have unusually large two-photon absorptivities (sigmaTPA), i.e., sigmaTPA approximately 10(2) GM. The authors tested this claim. Ultrafast two-photon absorption (TPA) spectroscopy was performed on solutions of hemoglobin, which contains a naturally occurring metaloporphyrin. They used a pump-probe technique to di...