Gastro-intestinal carcinoids are slow growing tumors arising from enterochromaffin or Kulchitsky cells. Their clinical presentation depends on what combination of bioactive substances is secreted. Midgut carcinoid can present with the carcinoid syndrome in the presence of liver metastases. Its most typical clinical manifestations include cutaneous flushing and diarrhea. A nonspecific biochemica...

• In 2007, our laboratory published an article in Clinical ncer Research reporting on the development of a human idgut carcinoid tumor cell line (1). This cell line has now en shared with over 20 laboratories around the world. vestigators in the field of neuroendocrine tumor rearch are aware that there are very few human carcinoid ll lines available for use in vitro and for murine studies. the ...

1. Raslan WF, Ro JY, Ordonez NG, Amin MB, Troncoso P, Sella A, et al. Primary carcinoid of the kidney. Immunohistochemical and ultrastructural studies of five patients. Cancer. 1993;72: 2660–6. 2. Krishnan B, Truong LD, Saleh G, Sirbasku DM, Slavin KM. Horseshoe kidney is associated with an increased relative risk of primary renal carcinoid tumor. J Urol. 1997;157:2059–66. 3. Gross MI, Berger I...

Bronchial carcinoid tumours are carcinoid tumours primarily occurring in relation to a bronchus. They are uncommon comprising only 1-2% of all lung tumours. This is case of 28 year old man with persistent wheezing, cough with expectoration, fever and chest pain on left side, for four to five months. All routine investigations were within normal limits. Chest roentgenogram demonstrated partial v...

Gastrointestinal carcinoid tumors date back to 1888 when Otto Lubarsch found multiple tumors in the distal ileum of two patients at autopsy (Lubarsch, 1888). The German pathologist Siegfried Oberndorfer was the first who used the term “Karzinoide Tumoren”, the English translation of which is “carcinoid tumor”. He coined this term because these tumors behaved less aggressively than true carcinom...

INTRODUCTION Neuroendocrine tumors are the second most common neoplasms of the larynx. Histopathologically, neuroendocrine tumors can be classified into four types: typical carcinoid tumors, atypical carcinoid tumors, small cell neuroendocrine tumors and paragangliomas. Typical carcinoid tumor of the larynx is a particularly rare occurrence. We present a case of this rare disease, and review an...

PURPOSE To report the anesthetic management of a patient with carcinoid tumour metastatic to the liver who presented for orthotopic liver transplantation. Anesthetic implications of metastatic carcinoid tumour on liver transplantation and the use of octreotide are discussed. CLINICAL FEATURES A 51-yr-old woman with intestinal carcinoid tumour metastatic to the liver presented for orthotopic l...

BACKGROUND Tumors of the minor papilla of the duodenum are extremely rare, and they are mostly neuroendocrine tumors, such as somatostatinomas and carcinoid tumors. However, true incidence of carcinoid tumors in minor papilla might be much higher, because patients with minor papillary tumors usually remain asymptomatic. We report a very unusual case of carcinoid tumor in a patient with complete...

INTRODUCTION Carcinoid tumors are the most common type of small bowel tumor, and the incidence is rising. The majority of small bowel carcinoid tumors arise within 60 cm of the ileocecal valve. The addition of ileoscopy to screening colonoscopy can detect asymptomatic small bowel carcinoid tumors and improve long-term prognosis through early surgical resection. Ileoscopy is a brief procedure wi...

BACKGROUND The association of bronchial carcinoid tumours with carcinoid syndrome is extremely rare especially in the absence of metastasic disease, and the angioedema is not a typical sign of this syndrome. METHODS AND RESULTS We report the case of a 39 year-old woman referred to our allergy department with recurrent episodes of angioedema. The aetiological study of angioedema did not show e...