UNLABELLED Variant angina presenting acute chest pain and ST elevation on electrocardiogram accounts for an underdiagnosed scenario in acute coronary syndrome and contributes to syncope as a consequence of ventricular arrhythmia. Here, we report a case of a 48-year-old man with a recent onset of chest pain and palpitations followed by syncope. Holter monitoring documented 2 episodes of evolving...

OBJECTIVES This study assessed the heart variability response to orthostatic stress during tilt table testing before and after normal saline administration. BACKGROUND The efficacy of sodium chloride and mineralocortoid in the treatment of neurally mediated cardiac syncope is attributed to intravascular volume expansion; however, their modulation of autonomic nervous system activity has not b...

BACKGROUND The wide range of clinical presentation of orthostatic vasovagal syncope suggests different underlying changes in the cardiac autonomic modulation. METHODS AND RESULTS To evaluate the beat-by-beat modifications in the neural control of heart period preceding a syncopal event, we studied RR interval variability in 22 healthy subjects who experienced fainting for the first time durin...

Background—This study was performed to compare implantation of a DDI pacemaker with rate hysteresis with no implant in respect to syncopal recurrences in patients with severe cardioinhibitory tilt-positive neurally mediated syncope. Methods and Results—Forty-two patients from 18 European centers were randomized to receive a DDI pacemaker programmed to 80 bpm with hysteresis of 45 bpm (19 patien...

BACKGROUND The dynamic autonomic processes leading to vasovagal syncope are poorly understood. METHODS AND RESULTS We used complex demodulation to continuously assess changes in respiration, R-R interval, and arterial pressure (blood pressure) variability during 60 degree head-up tilt in 25 healthy subjects with tilt-induced vasovagal syncope and 25 age-matched nonsyncopal control subjects. C...

Cardiac fibroma is a rare primary tumor of the heart. Patients can be asymptomatic or present with palpitations, cardiac murmur, syncope, arrhythmias, symptoms of congestive heart failure, or sudden death. We report a case of successful surgical excision of a giant cardiac fibroma in an asymptomatic child. Eur Res J 2018;4(1):52-54

INTRODUCTION Cardiac amyloidosis is an infiltrative cardiomyopathy in which amyloid protein is deposited throughout the myocardium. It is increasingly recognized as a cause of heart failure with preserved ejection fraction in the elderly. Presenting symptoms include exercise intolerance, fatigue, angina, breathlessness and syncope or pre-syncope.1 Atrial fibrillation is the most common early ar...

Elucidating the underlying cause of unexplained syncope, palpitations or other possible arrhythmia-related symptoms is a formidable clinical challenge. Cardiac monitoring supplements the most important "test" in patients with syncope or palpitations, that of a thoughtful history and physical examination. Ideally, comprehensive physiologic monitoring during spontaneous symptoms would constitute ...

Coronary anomalies are relatively common but rarely associated with syncope, myocardial ischemia, and sudden cardiac death. An anomalous right coronery artery from the left sinus of valsalva is now recognized as an important causative factor in sudden death and myocardial infarction and syncope.This case report presents an anomalous right coronary artery (RCA) originating from the left sinus of...

Cough syncope is a well-recognized syndrome in which loss of consciousness follows a bout of prolonged coughing. The pathophysiology of this syndrome has been attributed to lowered cerebral perfusion pressure consequent on an increased intrathoracic pressure, which lowers cardiac output (by a Valsalva mechanism) and impairs cerebral venous return. We report a case of cough-induced syncope in wh...