SR-BI is a cell surface HDL receptor that mediates selective uptake of the lipid cargo of HDL, an important process in hepatocytes, driving reverse cholesterol transport from cells in the artery wall. To facilitate examination of factors that modulate SR-BI activity in hepatocytes, we have generated fluorescent protein-tagged versions of SR-BI that allow for facile monitoring of SR-BI protein l...

Private Sector Development Department ▪ Vice Presidency for Finance and Private Sector Development Before Argentina began reforming port operations in 1990, its ports were costly and inefficient. Restrictive labor regulations led to high labor costs. Most ports were open rather than terminal-based, leading to inefficient operating practices and unnecessary costs for cargo handling and storage. ...


 Facilities at the airport are divided into two main parts consisting of land side and air side. Existing facilities on consist of: passenger terminal, cargo operational building, traffic control tower or Air Traffic Control (ATC), SAR (Search Rescue) meteorological main/VIP class entrance , fueling as well administrative office buildings. While runways, taxiways, aircraft parking areas, ...

Compared to cargo terminals, performance evaluation of cruise terminals sits in a backseat the current port studies, particularly Northeast Asia. This paper aims evaluate major Asia, taking into account important dimensions and criteria influencing terminal development, using primary data by experts' responses questionnaire survey. Complementary are also acquired field trips interviews find hid...

It is proposed to evaluate various options for the mooring of a vessel at berth cargo terminal by integer time intervals, which, when using Erlang's formulas, generalized case Markov process, can be used solve problems planning loading and unloading operations on company's ships, should presented in form vector, size which determined number possible states "ship – berth" system.
 A method ...

We consider a real-world cargo assembly planning problem arising in a coal supply chain. The cargoes are built on the stockyard at a port terminal from coal delivered by trains. Then the cargoes are loaded onto vessels. Only a limited number of arriving vessels is known in advance. The goal is to minimize the average delay time of the vessels over a long planning period. We model the problem in...

We evaluated 10 years of reported hazardous cargo incident information from the U.S. Air Force and Naval Safety Centers. In this first of two papers describing the hazardous cargo problems reported by the two services, we describe types of aircraft and types of hazardous cargo involved in incidents not causing aircraft mishaps. Normally, hazardous cargo must be manifested as such and no passeng...

The myosins are a large family of actin-binding motor proteins that convert stored chemical energy into work, with important functions in intracellular transport, force generation, and mechanosensation (1). Despite many advances in understanding the mechanical and kinetic properties of purified myosins in vitro, the signals that regulate the functions of these molecular motors in cells are not ...

Autophagy is a process delivering cytoplasmic components to lysosomes for degradation. Autophagy may, however, play a role in unconventional secretion of leaderless cytosolic proteins. How secretory autophagy diverges from degradative autophagy remains unclear. Here we show that in response to lysosomal damage, the prototypical cytosolic secretory autophagy cargo IL-1β is recognized by speciali...

Cells transport integral membrane proteins between organelles by sorting them into vesicles. Cargo adaptors act to recognize sorting signals in transmembrane cargos and to interact with coat complexes that aid in vesicle biogenesis. No coat proteins have yet been identified that generate secretory vesicles from the trans-Golgi network (TGN) to the plasma membrane, but the exomer complex has bee...