نتایج جستجو برای: cd2 removal
تعداد نتایج: 144924 فیلتر نتایج به سال:
We observed that certain E-receptor antibodies (CD2 antibodies) can induce proliferation of resting human T cells in the presence of PMA, while other CD2 antibodies fail to have such an effect. The same CD2 antibodies that were mitogenic in the presence of PMA (9.6, X11, VIT13), but not the nonreactive ones, were also able to induce T cell proliferation via the so-called alternative pathway of ...
Membrane nanotubes are thin membranous projections that physically connect two cells. While nanotubes have been studied in human natural killer (NK) cells and are implicated in aiding NK cell cytotoxic function, requirements for their formation to susceptible target cells remain incompletely understood. Here we demonstrate that the CD2-CD58/48 receptor-ligand interaction promotes and is require...
The goal of this study was to determine whether a substantial decrease in adult neurogenesis influences epileptogenesis evoked by the intra-amygdala injection of kainic acid (KA). Cyclin D2 knockout (cD2 KO) mice, which lack adult neurogenesis almost entirely, were used as a model. First, we examined whether status epilepticus (SE) evoked by an intra-amygdala injection of KA induces cell prolif...
ترکیب جدید (N2,N6-di(thiazol-2-yl)pyridine-2,6-dicarboxamide(DPD 2-نیتروژن، 6-نیتروژن دی (تیازول-2-ایل) پیریدین-2 و 6-دی کربوکسیلامید با استفاده از واکنش بین 2-آمینوتی ازول و پیریدین دیکربوکسیلیک اسید سنتز شد. ساختار DPD با تجزیه عنصری، طیفسنجی فروسرخ (FT-IR) و رزونانس مغناطیسی هسته (1HNMR) بررسی و تأیید شد. قابلیت حذف یونهای فلزات سنگین (Cd2+ و Zn2+) از محلول، با DPD مورد مطالعه قرار گرفت. ...
بسیاری از پسابهای صنعتی حاوی آلایندههای کاتیونی متنوعی از جمله فلزات سنگین و رنگهای آلی با ساختارهای تجریهناپذیر هستند که تهدید جدی برای سلامت عمومی و محیط زیست بهشمار میروند. در مطالعه حاضر نانوجاذبهای اکسید گرافن (GO) و اکسید گرافن اصلاح شده با 3-آمینو پروپیل تری اتوکسی سیلان (GO-NH2) به منظور حذف یونهای فلزی سرب (Pb2+)، کادمیوم (Cd2+) و رنگ کاتیونی متیلنبلو (MB) در محلولهای آبی د...
Relapsed or refractory Burkitt's lymphoma often has a poor prognosis in spite of intensive chemotherapy that induces apoptotic and/or necrotic death of lymphoma cells. Rapamycin (Rap) brings about autophagy, and could be another treatment. Further, anti-CD19-targeted liposomal delivery may enable Rap to kill lymphoma cells specifically. Rap was encapsulated by anionic liposome and conjugated wi...
In rats, of the Wistar-Porton strain, a single intravenous injection of 1.25 mg Cd2+ between days 9 and 15 of gestation results in a high incidence (80% of hydrocephalus, together with other malformations in the fetuses, examined on day 20. This dose is critical, since 1.1 mg Cd2+/kg is not teratogenic, while 1.35 mg Cd2+/kg kills all the embryos. Intravenous injection of Cd2+ to the pregnant r...
The CD58 binding site on human CD2 was recently shown by nuclear magnetic resonance structural data in conjunction with site-directed mutagenesis to be a highly charged surface area covering approximately 770A2 on the major AGFCC'C" face of the CD2 immunoglobulin-like (Ig-like) NH2-terminal domain. Here we have identified the other binding surface of the CD2-CD58 adhesion pair by mutating charg...
We have shown previously that primary dendritic cells and monocytes express equal levels of CD14 but are distinguishable by the presence of CD2 on dendritic cells. CD2 is known to mediate the activation of T and natural killer (NK) cells through its interaction with CD58. CD2 epitopes recognized by anti-T111, -T112, and -T113 monoclonal antibodies (mAbs) are present on dendritic cells. Here we ...
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