نتایج جستجو برای: cd4 cd8 ratio
تعداد نتایج: 580064 فیلتر نتایج به سال:
On the non-autoimmune C57BL/6 (B6) background, the chromosome 7-derived lupus susceptibility loci Sle3 and Sle5 have been shown to mediate an elevated CD4:CD8 ratio with an increase in activated CD4(+) T cells, decreased susceptibility to apoptosis, and a break in humoral tolerance. Development of subcongenic strains has subsequently shown that the elevated CD4:CD8 ratio is due to Sle3 but that...
INTRODUCTION Pleural effusion induced by sarcoidosis is rare, and pleural sarcoidosis is often diagnosed by thoracoscopic surgery. The diagnosis of pleural sarcoidosis using thoracentesis may be less invasive when sarcoidosis is already diagnosed histologically in more than one organ specimen. Here we report the case of a 64-year-old woman with pleural sarcoidosis diagnosed on the basis of an i...
Plasma HIV viral load is related to declining CD4 lymphocytes. The extent to which CD8 cells, in addition to RNA viral load, predict the depletion of CD4 cells is not well characterized so far. We examine if CD8 cell count is a prognostic factor for CD4 cell counts during an HIV infection.A longitudinal analysis is conducted using data from the Swiss HIV cohort study collected between January 2...
Background. Colorectal cancer (CRC) is one of the most common malignant neoplasms in world. It ranks third structure oncological morbidity and second mortality. The liver site metastatic spread CR 14 to 18% patients have metastases at diagnosis. Radiofrequency ablation currently promising method treating lesions.
 Рurpose – study quantitative changes hematoimmunological indicators their in...
Background & Aim: There are many suggestions for nasal polyp formation mechanism. The present study was carried out to evaluate T-cell infiltration in nasal mucosa and specific allergic reactions in context of probable irregular systemic immune responses in nasal polyp disease. Patients & Methods: 60 patients with nasal polyps who referred to ENT ward of Rasoul-e-Akram Hospital were studied...
سابقه و هدف: مایکوتوکسین T-2 با آلودهسازی غلات و علوفه موجب مسمومیت انسان و دام میشود و روی سلولهای سیستم ایمنی نیز اثرات جدی بر جای میگذارد. هدف این مطالعه، بررسی سینتیک تغییرات جمعیت لنفوسیتی خون محیطی موش پس از تزریق سم T-2 بود. مواد و روشها: این مطالعه از نوع تجربی است. دز تحت کشنده سم T-2 برای موش تعیین و به گروههای مختلف تزریق شد. در ساعات 12، 24، 48 و 72 پس از تزریق، از موشها...
Flow cytometer (FACScan) was used to determine the range of T lymphocyte subpopulations in normal Thai blood donors at Maharaj Nakorn Chiang Mai Hospital, Chiang Mai. Reference population consisted of 150 healthy HIV seronegative blood donors. T lymphocyte subsets were analysed using two-color immunophenotyping of peripheral blood lymphocytes with a lysed whole blood technique and enumerated. T...
Thymic atrophy is a prominent feature of malnutrition. Forty-eight hours' starvation of normal mice reduced the total thymocyte count to 13% of that observed in freely fed controls, predominantly because of a diminution in the cortical CD4(+)CD8(+) thymocyte subpopulation. Prevention of the fasting-induced fall in the level of the adipocyte-derived hormone leptin by administering exogenous reco...
The aim of the present study was to determine whether the sensitivity of thymocytes to X-ray radiation depends on their proliferative states and whether radiation impairs the maturation of donor-derived thymocytes in recipient thymus. We assigned 8-week-old C57BL/6J mice into three treatment groups: 1) untreated; 2) X-ray radiation; 3) X-ray radiation plus bone marrow transplantation with donor...
BACKGROUND HIV-infected individuals have deficient responses to Yellow Fever vaccine (YFV) and may be at higher risk for adverse events (AE). Chronic immune activation-characterized by low CD4/CD8 ratio or high indoleamine 2,3-dioxygenase-1 (IDO) activity-may influence vaccine response in this population. METHODS We prospectively assessed AE, viremia by the YFV virus and YF-specific neutraliz...
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