background : â  celiac disease (cd) is an immune-mediated inflammation of the small intestine caused by sensitivity to dietary gluten and related proteins in genetically sensitive individuals . recurrent aphthous stomatitis (ras) is an inflammatory condition characterized by painful recurrent, single or multiple ulcerations of the oral mucosa. the association between cd and ras has been evaluat...

OBJECTIVE To assess the prevalence of headache in clinic and support group patients with celiac disease and inflammatory bowel disease (IBD) compared with a sample of healthy controls. BACKGROUND European studies have demonstrated increased prevalence of headache of patients with celiac disease compared with controls. METHODS Subjects took a self-administered survey containing clinical, dem...

BACKGROUND Celiac disease is an immune-mediated disorder elicited by ingestion of gluten in genetically susceptible persons. This disorder is characterized by specific histological changes of the small intestine mucosa resulting in malabsorption. This case was written up as it was an unusual and dramatic presentation of celiac disease. CASE PRESENTATION We report the case of a 3-year-old Alba...

Even though MHC class II is a dominant susceptibility factor for many diseases, culprit T cell epitopes presented by disease-associated MHC molecules remain largely elusive. T cells of celiac disease lesions recognize cereal gluten epitopes presented by the disease-associated HLA molecules DQ2.5, DQ2.2, or DQ8. Employing celiac disease and complex gluten Ag digests as a model, we tested the fea...

OBJECTIVE Gastrointestinal symptoms are a common feature in children with autism, drawing attention to a potential association with celiac disease or gluten sensitivity. However, studies to date regarding the immune response to gluten in autism and its association with celiac disease have been inconsistent. The aim of this study was to assess immune reactivity to gluten in pediatric patients di...

At present there is a degree of uncertainty regarding when, how and in what form gluten should be introduced into the infant diet. For years the recommendations of the ESPGHAN Committee on Nutrition have prevailed, which include avoiding early introduction, before 4 months, and late, after 7 months, and gradually introducing gluten into the diet while the infant is being breastfed, with the aim...

November 01, 2008 Celiac disease (sprue) is a gluten-sensitive enteropathy of the gastrointestinal tract that affects the small intestine in individuals who are genetically susceptible. It is characterized by small intestinal malabsorption after the ingestion of gluten, villous atrophy of the small intestinal mucosa with increased intraepithelial lymphocytes, clinical and histologic improvement...

The prevalence of celiac disease is rising. As a result there is increasing interest in the associated mortality and morbidity of the disease. Screening of asymptomatic individuals in the general population is not currently recommended; instead, a strategy of case finding is the preferred approach, taking into account the myriad modes of presentation of celiac disease. Although a gluten-free di...

A strict gluten-free diet (GFD) is the only currently available therapeutic treatment for patients with celiac disease, an autoimmune disorder of the small intestine associated with a permanent intolerance to gluten proteins. The complete elimination of gluten proteins contained in cereals from the diet is the key to celiac disease management. However, this generates numerous social and economi...

version of a paper published in Clinical and experimental immunology. This paper has been peer-reviewed but does not include the final publisher proof-corrections or journal pagination. "Reduction of tissue transglutaminase autoantibody levels by gluten-free diet is associated with changes in subsets of peripheral blood lymphocytes in children with newly diagnosed coeliac disease" Reduction of ...