نتایج جستجو برای: cell contact

تعداد نتایج: 1824576  

Journal: :Progress in Biophysics and Biophysical Chemistry 1960

Journal: :Journal of cell science 2004
Bradley W Doble Xitong Dang Peipei Ping Robert R Fandrich Barbara E Nickel Yan Jin Peter A Cattini Elissavet Kardami

Mitogenic stimulation of cardiomyocytes is associated with decreased gap junction coupling and protein kinase C (PKC)-mediated phosphorylation of the gap junction protein connexin43 (Cx43). Identification of and interference with the amino acid(s) that becomes phosphorylated in response to stimulation are important steps towards defining the relationship between Cx43 phosphorylation and cell cy...

2015
Christine Chiasson-MacKenzie Zachary S. Morris Quentin Baca Brett Morris Joanna K. Coker Rossen Mirchev Anne E. Jensen Thomas Carey Shannon L. Stott David E. Golan Andrea I. McClatchey

The proliferation of normal cells is inhibited at confluence, but the molecular basis of this phenomenon, known as contact-dependent inhibition of proliferation, is unclear. We previously identified the neurofibromatosis type 2 (NF2) tumor suppressor Merlin as a critical mediator of contact-dependent inhibition of proliferation and specifically found that Merlin inhibits the internalization of,...

Journal: :Proceedings for Annual Meeting of The Japanese Pharmacological Society 2018

Journal: :Plastic and Reconstructive Surgery Global Open 2013

Journal: :The Journal of Cell Biology 1999
Irina Kaverina Olga Krylyshkina J. Victor Small

We recently showed that substrate contact sites in living fibroblasts are specifically targeted by microtubules (Kaverina, I., K. Rottner, and J.V. Small. 1998. J. Cell Biol. 142:181-190). Evidence is now provided that microtubule contact targeting plays a role in the modulation of substrate contact dynamics. The results are derived from spreading and polarized goldfish fibroblasts in which mic...

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