background: for xenograft models of triple-negative breast cancer (tnbc) to be valuable in development of molecularly-targeted drugs, careful characterization is essential to their validation. the present study aimed to validate the tnbc xenograft model with a specific focus on angiogenesis. methods : twelve tnbc xenograft tumors and 12 human breast cancer tumors (htnbc) were included in this s...

BACKGROUND Understanding of the interplay between plasma HIV RNA level and CD4 cell count depletion in untreated infection remains incomplete. METHODS We studied 1169 people with HIV seen for care at a major London clinic while naive to antiretroviral therapy. We considered pairs (n = 5940) of consecutive simultaneously measured CD4 cell count and plasma HIV RNA values from patients who had n...

nowadays, cell -based and tissue engineered products have opened new horizons in treatment of incurable nervous system disorders. the number of studies on the role of schwann cells (sc) in treating nervous disorders is higher than other cell types. different protocols have been suggested for isolation and expansion of sc which most of them have used multiple growth factors, mitogens and fetal b...

BACKGROUND White blood cell count is an independent risk factor for cardiovascular disease. Several lifestyle and metabolic factors such as cigarette smoking and obesity are known to be associated with an elevated white blood cell count. However, the joint effect of cigarette smoking and obesity on white blood cell count has not yet been fully described. METHODS We explored the joint effect o...

This retrospective study investigated the correlations between red blood cell (RBC) count, hemoglobin, and hematocrit on admission, and mortality in 140 patients with subarachnoid hemorrhage (SAH). Correlations between the hematological parameters RBC count, hematocrit, hemoglobin, white blood cell (WBC) count, and platelet count on admission and mortality were investigated. Association of each...

Ten healthy controls, 9 Rheumatoid Arthritis patients and 5 cancer patients were studied for T and B cells in peripheral circulation. T cell count in cancer patients showed a slight enhancement after receiving Ayurvedic Treatment; but the B cell count remained the same. In Rheumatoid Arthritis patients no significant change was noticed either in T cell or cell count.

BACKGROUND Estimates of the decrease in CD4(+) cell counts in untreated patients with human immunodeficiency virus (HIV) infection are important for patient care and public health. We analyzed CD4(+) cell count decreases in the Cape Town AIDS Cohort and the Swiss HIV Cohort Study. METHODS We used mixed-effects models and joint models that allowed for the correlation between CD4(+) cell count ...

tramadol is a synthetic, centrally acting opioid analgesic that has the best analgesic efficacy without excessive sedation and significant side effects in the postoperative pain relief in dogs. objectives: in this study, hematological and biochemical changes due to short usage of tramadol were assessed in clinically healthy dogs. methods: for this purpose, eighteen male mongrel dogs aged 14 to ...