background: the present study was performed to investigate the effects of trace elements particularity se, zn and cu on tumor genesis in breast cancer. methods: the inhibitory effect of se, zn and cu, on telomerase activity was analyzed in human breast tumor tissues and breast cancer (t47d) cells. tissue specimens from 24 women with benign breast disease and 32 women with breast cancer specimen...

Background: Today, the use of maggot therapy has become widespread due to the increase in chronic ulcers in the world. The recombinant production of secreted enzymes from these larvae is a novel non-invasive method for the treatment of chronic ulcers. Lucilia sericata (L. sericata) collagenase (MMP-1) has been expressed in insect cells. Collagenase is an enzyme that is widely used in clinical t...

T h e comple te pos tembryon ic ceil l ineages of the free-l iving nenta todes Caenorhabditis elegans and Panagrellus redivivus are known. Pos tembryonic cell divisions lead to subs tan t ia l increases in the n u m b e r of cells and, in mos t cases, in the n u m b e r of types of cells in the neurona l , muscu la r , hypodermal , and digestive systems. T h e pa t te rns of pos tembyron ic cel...

Neurodegenerative disorders such as Parkinson’s disease, motor neuron disease and Alzheimer’s disease is characterized by loss of specific cells within certain regions of the brain. One of the most compelling questions is to determine why specific cell populations are vulnerable to neurodegeneration. We addressed this question by studying global gene expression changes using an animal model of ...

Neurodegenerative disorders such as Parkinson’s disease, motor neuron disease and Alzheimer’s disease is characterized by loss of specific cells within certain regions of the brain. One of the most compelling questions is to determine why specific cell populations are vulnerable to neurodegeneration. We addressed this question by studying global gene expression changes using an animal model of ...

T h e comple te pos tembryon ic ceil l ineages of the free-l iving nenta todes Caenorhabditis elegans and Panagrellus redivivus are known. Pos tembryonic cell divisions lead to subs tan t ia l increases in the n u m b e r of cells and, in mos t cases, in the n u m b e r of types of cells in the neurona l , muscu la r , hypodermal , and digestive systems. T h e pa t te rns of pos tembyron ic cel...

background & aim: investigation of suspension cell culture and callus production in catharanthus roseus. catharanthus roseus is an herbaceous perennial plant belongs to the family apocynaceae. c. roseus is important as commercial medicinal plant because of its alkaloidal content. whole plant contains about 130 alkaloids those are classified as vinca alkaloids. vincristine and vinblastine; t...

The new anti-cancer and water-soluble curcumin derivatives have been synthesized solvent-freely by functionalizing the phenolic group of with various NH compounds to increase water solubility cancerous properties. biological applications drugs investigated against highly potent HepG2 carcinoma cell line. studies showed that could be used in low concentrations (µM/l<1) avoid anti-apoptoti...