The diverse manifestations of CELL-MEDIATED IMMUNITY (CMI) include several mechanisms by which target cells may be killed. The induction of one of these mechanisms, namely killing by CYTOTOXIC T-CELLS, involves the participation of two distinct, antigenically precommitted lymphocytes (THand TC -cellCELLS) as well as non-specific antigen-presenting cells (APCs, typified by DENDRITIC CELLS and MA...