Cherubism is a familial disease of the jaws which is inherited via autosomal dominant manner. Typical features of cherubism include a painless bilateral, symmetrical enlargement of the jaws, misalignment of teeth, and intra-osseous central giant cell granuloma-like lesions, which are usually evident in early childhood. Treatment of cherubism consists of local curettage of the lesions, jaw conto...

Background and Importance Giant cell granuloma (GCG) is a rare, benign, non-neoplastic lesion of the head and neck. More common in the jaw bones, there have been few reports of the lesion arising in the temporal bone. Initially referred to as a "giant cell reparative granuloma," due to the previously accepted notion of its nature in attempting to repair areas of injury, the term "giant cell gra...

Central hemangioma, a bone destructive lesion, is a benign tumor. Hemangiomas of jaws are rare entity and produces many different radiographic images. Radiographic differential diagnosis includes osteosarcoma, fibrous dysplasia, central giant cell granuloma, ameloblastoma, odontogenic myxoma, multiple myeloma, dentigerous cyst and aneurysmal bone cyst. Since it involves proliferation of blood v...

Peritoneal keratin granuloma is a rare lesion included under granulomatous lesions of the peritoneum. It can be of infectious and non-infectious etiology. The lesion presents as a large intra-abdominal necrotic mass often misinterpreted clinically as a disseminated carcinoma. We report a case of peritoneal keratin granuloma in a 50-year-old male following peritonitis. Histomorphology revealed l...

A case of a rare giant cell lesion of a tarsal bone, giant cell reparative granuloma, is presented with CT correlation. CT is useful in pre-operative management both in defining the extent of involvement of adjacent structures and demonstrating soft tissue abnormality.

INTRODUCTION Peripheral giant cell granuloma and peripheral ossifying fibroma are clinicopathologically distinct gingival lesions. Both are included in clinical differential diagnoses of common benign and reactive gingival epulides in humans. It is often impossible to make a clinical distinction between the two entities, thereby making definitive diagnosis dependent on histopathologic features....

Giant cell tumor (GCT) of bone is a giant-cell-rich bony lesion associated with abundant multinucleated osteoclast-type giant cells. It is a primary neoplasm of bone with characteristic clinical, radiological, and pathological features. It is an expansive and lytic lesion without periosteal reaction and prominent peripheral sclerosis. Giant cells are also seen in other diseases like giant cell ...