Leber's hereditary optic neuroretinopathy (LHON) is manifested as a bilateral acute or subacute loss of central vision due to optic atrophy. It is linked to point mutations of mitochondrial DNA, which is inherited maternally. The most common mitochondrial DNA point mutations associated with LHON are G3460A, G11778A and T14484C. These mutations are linked with the defects of subunits of the comp...

Dear Editor, Optic neuritis is the most common inflammatory optic neuropathy affecting young adults [1]. Less commonly, optic neuritis may be associated with systemic autoimmune disease, of which Behçet’s syndrome is an extremely rare cause, with only 20 identified cases to date [2]. To the best of our knowledge, there have been no reports in Korean patients. Herein, we report a patient present...

PURPOSE To describe new, efficient predictors of maximum reading speed (MRS) in age-related macular degeneration (AMD) patients with central field loss. Type of AMD (wet versus dry) was scrutinized, because this factor seems to offer a promising model of differential visual adaptation induced by different temporal courses of disease progression. METHODS Linear mixed-effects (LME) analyses wer...

OBJECTIVE No method of grading visual field (VF) defects has been widely accepted throughout the glaucoma community. The SCHEIE (Systematic Classification of Humphrey visual fields-Easy Interpretation and Evaluation) grading system for glaucomatous visual fields was created to convey qualitative and quantitative information regarding visual field defects in an objective, reproducible, and easil...

Central serous chorioretinopathy (CSC) is a relatively common posterior segment disease characterized by serous detachment of the neurosensory retina. Altered function of the retinal pigment epithelium (RPE) and choroidal vascular hyperpermeability suggestive of choroidal vascular compromise have been thought to play important roles in the pathogenesis of CSC [1,2]. CSC typically affects middle...

The sustained component of visual attention lowers the perceptual threshold of stimuli located at the attended region. Attentional performance is not equal for all eccentric positions, leading to variations in perception. The location of the preferred retinal locus (PRL) for fixation might be influenced by these attentional variations. This study investigated the relation between the placement ...

Crowding is thought to be one potent limiting factor of reading in peripheral vision. While several studies investigated how crowding between horizontally adjacent letters or words can influence eccentric reading, little attention has been paid to the influence of vertically adjacent lines of text. The goal of this study was to examine the dependence of page mode reading performance (speed and ...

BACKGROUND The purpose of this paper is to study the spatial agreement between visual field defects and ultra-wide field (UWF) fundus autofluorescence (FAF) in patients with birdshot chorioretinopathy (BSCR). The study is a retrospective, cross-sectional analysis of a university uveitis practice. Eight (8) eyes of five (5) patients with BSCR were included. Inclusion criteria were ability to fix...

OBJECTIVE To report the clinical presentation of malarial retinopathy in an adult, emphasizing the importance of this diagnosis for the clinical suspicion and prognosis of cerebral malaria. METHODS A 39-year-old caucasian man presented with hemolytic anemia, thrombocytopenia, acidemia and acute renal failure, developing severe encephalopathy. The diagnosis of Plasmodium falciparum malaria was...