introduction: development of brain edema following focal cerebral ischemia exacerbates primary ischemic injury. blood brain barrier (bbb) opening is an important part of edema named as vasogenic brain edema. in this study, quantitative alterations of bbb permeability is experimentally evaluated using transient focal cerebral ischemia in the rat. methods: two groups of male rats (ischemic and sh...

introduction: the efficiency of muscular function is directly related to energy consumption. maintaining the dynamic equilibrium and fatigue during walking and other daily activities are the main problems in spastic cerebral palsy patients. recognition of mechanism and muscular function in these patients is important from a clinical and rehabilitational perspective. the objective of this study ...

cerebral venous thrombosis, including thrombosis of cerebral veins and major dural sinuses, is an uncommon disorder in the general population. however, it has a higher frequency among patients younger than 40 years of age, patients with thrombophilia, pregnant patients or those receiving hormonal contraceptive therapy or has foreign body such as catheter in their veins or arterial system. in th...

in this paper it has been shown that deterioration of the brain cortex capillary system and negative dynamics of cerebral tissue morphology occur under conditions of hypo kinesia. simultaneously, gamma-aminobutyric acid (gaba) and piracetam have been shown to favor the development of vasodilation and prevent further worsening of the cerebral blood supply. during the experiment, it was also esta...

Background: The role of nitric oxide (NO) of endothelial or neuronal origins in cerebral ischemia and reperfusion injuries are far from being settled, extending from being important to not having any role at all.  Objective: To investigate the role of NO of endothelial and neuronal origins in ischemia/reperfusion injuries in focal cerebral ischemia, L-NAME, a non selective NO synthase inhibitor...

objective(s): stroke poses a crucial risk for mortality and morbidity. our study aimed to investigate the effect of p-coumaric acid on focal cerebral ischemia in rats. material and methods: rats were randomly divided into four groups, namely group i (control rats), group ii (ischemia rats), group iii (6 hr ischemia + p-coumaric acid rats) and group iv (24 hr ischemia + p-coumaric acid rats). ce...

objectives: this study aimed to evaluate the effectiveness of psycho-rehabilitation (dohsa-hou) on improving the quality of life of 4-12 year old children with cerebral palsy. methods: the present research is a semi-experimental study with a pre-test - post-test design, follow-up and control group. the statistical population fully consists of children with cerebral palsy in yazd. 30 male patien...

background: centre of pressure displacement is an indicator of postural control. children with cerebral palsy have poor postural control. one common intervention to enhance their balance is vestibular stimulation. the aim of this research was to investigate the effect of vestibular stimulation on cop parameters in children with cerebral palsy (3-10 years old). methods: this study was a randomiz...