The normal system of ordinary differential equations, whose right-hand sides are the ratios linear and nonlinear positive functions, is considered. A feature these that some their denominators can take on arbitrarily small nonzero values. (Thus, modules corresponding derivatives large value.) In sequel, constructed equations used to model strongly oscillating processes (for example, determined ...

Interneurons originating from the ganglionic eminence migrate tangentially into the developing cerebral wall as they navigate to their distinct positions in the cerebral cortex. Compromised connectivity and differentiation of interneurons are thought to be an underlying cause in the emergence of neurodevelopmental disorders such as schizophrenia. Previously, it was suggested that tangential mig...

Glutamate concentrations in striatum and cortex were measured by means of in vivo cerebral microdialysis before and for 4 h after middle cerebral and ipsilateral common carotid artery occlusion in rats. The peak glutamate concentration reached 7.28 +/- 3.60 microM in dialysate from striatum and 5.64 +/- 2.24 microM in that from cortex. An index of exposure of each region to glutamate was calcul...

We have considered how the neuronal network architecture of the hippocampus may enable it to act as an intermediate term buffer store for recent memories, and how information may be recalled from it to the cerebral cortex using modified synapses in back-projection pathways from the hippocampus to the cerebral cortex. The recalled information in the cerebral neocortex could then be used by the n...

Interneurons originating from the ganglionic eminence migrate tangentially into the developing cerebral wall as they navigate to their distinct positions in the cerebral cortex. Compromised connectivity and differentiation of interneurons are thought to be an underlying cause in the emergence of neurodevelopmental disorders such as schizophrenia. Previously, it was suggested that tangential mig...

Liver X receptor (LXR) beta regulates cholesterol levels in the brain and is essential for maintenance of motor neurons in the spinal cord and dopaminergic neurons in the substantia nigra. Here, we have examined the expression pattern of LXRbeta protein in the cerebral cortex and looked for defects in cortical development in LXRbeta knockout (LXRbeta(-/-)) mice. LXRbeta protein was widely expre...

BACKGROUND AND PURPOSE The ischemic brain may stimulate angiogenesis to compensate for impaired circulation. We examined the conditions promoting such angiogenesis to provide the basis for surgical treatment. METHODS The degree of cerebral hemodynamic stress was studied in patients with moyamoya disease using the stable xenon-enhanced computed tomographic acetazolamide tolerance test and posi...

The aim of the study was to age-related changes in cytoarchitectonics functionally different areas posterior associative cortex temporal and occipital lobes cerebral hemispheres children during first year life. Material methods. material included left male (39 observations) aged from birth 12 months who died accidents without brain damage. Using computer morphometry, thickness cortex, external ...

Investigations aimed to define the components of the cholinergic network in the cerebral cortex and their functional modifications under the effect of a number of psychotropic drugs are described. By measuring acetylcholine levels and acetylcholine output from the cerebral cortex in cats and rats with various subcortical lesions, at least two systems of cholinergic neurons ascending to the cort...

We determined the role of endogenous hydrogen sulfide (H2S) in cerebral vasodilation/hyperemia and early BBB disruption following ischemic stroke. A cranial window was prepared over the left frontal, parietal and temporal cortex in mice. Transient focal cerebral Ischemia was induced by directly ligating the middle cerebral artery (MCA) for two hours. Regional vascular response and cerebral bloo...