BACKGROUND Medical practice is a form of art, with each complex detail essential to the welfare of the individuals in the care of the physician. Art and medicine have shared a close relationship in a variety of ways for centuries, as demonstrated by anatomical drawings and textbooks from the 16th century. Leonardo da Vinci, driven by his fascination with the details of the human body and how it...

Neurocytomas are a rare subset of primary cerebral neuroblastomas. They occur within the ventricles of young adults, may calcify , and demonstrate a better prognosis than do their parenchymal counterparts . Of the 21 patients reported in the literature who appear to meet most of the criteria for th is diagnosis, 18 had symptoms referable to increased intracranial pressure [1-1 0]. The lesions w...

RD, Gershon S (eds) Neurobiology of Aging. Vol 3, New York, 22. Raven Press, 1976, pp 155-166 21. Roberts MA, Caird FI: Computerized tomography and intellectual impairment in the elderly. J Neurol Neurosurg 23. Psychiatry 39: 986-989, 1976 Barron SA, Jacobs L, Kinkel WR: Changes in size of normal lateral ventricles during aging determined by computerized tomography. Neurology (Minneap) 26: 1011...

We report on an 80-year-old woman who had shunt-responsive idiopathic normal pressure hydrocephalus (iNPH). Her brain MRI showed an initial change in the subarachnoid space (a disproportional narrowing of the subarachnoid space at the cerebral high convexities) at the age of 70 years, followed by enlargement of the ventricles (Evans index: 0.31) at the age of 78. The observation suggests that c...

RD, Gershon S (eds) Neurobiology of Aging. Vol 3, New York, 22. Raven Press, 1976, pp 155-166 21. Roberts MA, Caird FI: Computerized tomography and intellectual impairment in the elderly. J Neurol Neurosurg 23. Psychiatry 39: 986-989, 1976 Barron SA, Jacobs L, Kinkel WR: Changes in size of normal lateral ventricles during aging determined by computerized tomography. Neurology (Minneap) 26: 1011...

RD, Gershon S (eds) Neurobiology of Aging. Vol 3, New York, 22. Raven Press, 1976, pp 155-166 21. Roberts MA, Caird FI: Computerized tomography and intellectual impairment in the elderly. J Neurol Neurosurg 23. Psychiatry 39: 986-989, 1976 Barron SA, Jacobs L, Kinkel WR: Changes in size of normal lateral ventricles during aging determined by computerized tomography. Neurology (Minneap) 26: 1011...

This study proposes the implementation of a Multiple-Network Poroelastic Theory (MPET) model for the purpose of investigating in detail the transport of water within the cerebral environment. The advantage of using the MPET representation is that it accounts for fluid transport between CSF, brain parenchyma and cerebral blood. They key novelty in the model discussed in the present study is the ...

It has been hypothesized that white matter lesions at different locations may have different etiology and clinical consequences. Several approaches for the quantification of local white matter lesion load have been proposed in the literature, most of which rely on a distinction between lesions in a periventricular region close to the ventricles and a subcortical zone further away. In this work ...

BACKGROUND Clinicians use a non-standardized, intuitive approach when correlating radiological morphology and etiology of hydrocephalus. OBJECTIVE To investigate the possibility of categorizing hydrocephalus in different groups based on radiological morphology, to analyze if these proposed groups relate to the location and type of underlying pathology, and if this can be of use in clinical pr...

Results: We found significant decreases in crosssectional whole-brain (P .001), temporal lobe (P .001), and hippocampal (P=.003) volumes and a significant increase in ventricular volume (P .001) with increasing age. Cross-sectional and longitudinal estimates of atrophy rates were similar. We also found directional evidence of acceleration in atrophy rates with increasing age in all analyses, wi...