BACKGROUND Parity is well established as a risk factor for cervical cancer. It is not clear, however, how pregnancy influences the natural history of HPV infection and cervical neoplasia. Our objective was to study the risk of HPV infection and cervical squamous intraepithelial lesions (SIL) after pregnancy. METHODS We used the Ludwig-McGill cohort study which includes 2462 women recruited in...

Purpose To investigate the impact of adenomyosis on the complications and outcomes of pregnancy in Japan. Methods We carried out a multicenter retrospective questionnaire survey. A questionnaire regarding pregnancy complications and the outcomes of pregnancy was sent to 725 facilities. Results Data were obtained on the cases of 272 pregnant women with adenomyosis from 65 facilities. The com...

OBJECTIVE To examine the possible benefit of cervical cerclage in women with a very short cervix identified during routine sonographic assessment of cervical length at 23 weeks of gestation. METHODS Transvaginal sonography was used to measure cervical length at 23 weeks of gestation in 2702 women with singleton pregnancies attending for routine antenatal care. In 43 (1.6%) cases the cervical ...

Of all the rights of women, to become a mother is greatest. Nature has endowed every woman with the power of procreation. But how, at times, she has to suffer series of obstacles to achieve this goal, challenging her own life. Carcinoma Cervix is the most challenging cancer during pregnancy as the pregnant uterus itself is affected. It’s a challenge for all the mother, the family and the treati...

The exact mechanisms that regulate cervical softening or ripening during pregnancy are not completely understood. The aim of this study was to estimate the effects of various agents on cervical softening during pregnancy in rats. Cervical resistance was examined after treatment with nitric oxide (NO) donors and inhibitors and different hormonal agents. Cervical resistance was significantly redu...

BACKGROUND Nitric oxide (NO) is a factor in cervical ripening, perhaps under the control of progesterone. We studied the effects of the antiprogesterone mifepristone on the release of NO and on the expression of inducible NO synthase (iNOS) and endothelial NO synthase (eNOS) in the uterine cervix of women in early pregnancy. METHODS Thirteen women were treated with oral mifepristone (200 mg),...

Objective: To determine the immediate and late complications of women undergoing cervical cerclage, as well as their pregnancy outcomes. Methods: This was a retrospective study based on traceable patient records over a 9-year period (2000 to 2008) undertaken at the Kenyatta National Hospital, Kenya’s major referral and teaching hospital. All files on women diagnosed with cervical incompetence a...

OBJECTIVE To examine the potential value of routine measurement of cervical length in singleton pregnancies at 23 weeks of gestation in the prediction of the risk for early spontaneous preterm delivery. METHODS Cervical length was measured by sonography at 23 weeks in 2567 singleton pregnancies in women attending for routine antenatal care. In 43 women, the length was < or = 15 mm and 21 of t...

OBJECTIVE To determine the impact of cervical excision for cervical intraepithelial neoplasia on fertility and early pregnancy outcomes. DESIGN Systematic review and meta-analysis of cohort studies. DATA SOURCES Medline and Embase. ELIGIBILITY CRITERIA Studies assessing fertility and early pregnancy outcomes in women with a history of treatment for cervical intraepithelial neoplasia versu...

Background Preterm labor and birth are associated with several neonatal complications including respiratory distress syndrome and intraventricular hemorrhage. Differentiating true and false labor pain is a dilemma to obstetricians. Objective To elucidate the role of cervical length measurement in prediction of birth in pregnant women with threatened preterm labor. Materials and Methods In t...