Several genome-wide searches for disease-associated gene variations have been recently reported (Spinola et al, 2006; Herbert et al, 2006). However, complex diseases can be caused by combinations of several unlinked gene variations. Unfortunately, an exhaustive search among all possible corresponding multi-SNPs can be unfeasible even for small number of SNPs let alone the complete genome. Disea...

This paper presents an approach for generation of multilingual explanations from Conceptual Graphs (cgs) in restricted domains with highly conventional language. The generator is developed within a Knowledge Based Machine Aided Translation project DB-MAT. The system's objective is to provide the translator with the necessary domain knowledge. The algorithms handle extended referents, complex ty...

This study presents the temperature dependence of small signal parameters of GaN/SiC HEMTs across the 0–150◦C range. The changes with temperature for transconductance (gm), output impedance (Cds and Rds), feedback capacitance (Cdg), input capacitance (Cgs), and gate resistance (Rg) are measured. The variations with temperature are established for gm, Cds, Rds, Cdg, Cgs, and Rg in the GaN techno...

Clinical Guidelines (CGs) capture medical evidence, but are not meant to deal with single patients’ peculiarities and specific context limitations and/or constraints. In practice, the physician has to exploit basic medical knowledge (BMK) in order to adapt the general CG to the specific case at hand. The interplay between CG knowledge and BMK can be very complex. In this paper, we explore such ...

The problem of the reality of Compact Groups of galaxies (CGs) is discussed. We separated two classes of groups: elongated, chain-like groups (I), and round ones (II). The number of chain-like groups among Hickson Compact Groups (HCGs) is about twice as large as that of the round ones. In Shakhbazian Compact galaxy Groups (ShCGs) the proportion of chain-like groups is smaller than that of the r...

Abstract City Gate Stations (CGS) are critical elements of Natural Gas (NG) distribution systems, as they connect national high-pressure transmission networks with local low-pressure networks. One their main tasks is to pre-heat the gas avoid dangerous sub-cooling due Joule-Thompson effect after pressure reduction stage. For this process, significant amounts thermal energy required, usually obt...

This paper proposes optimal operational planning for cogeneration system (CGS) using particle swarm optimization (PSO). CGS is usually connected to various facilities such as refrigerators, reservoirs, and cooling towers. In order to generate optimal operational planning for CGS, startup/shutdown status and/or input/output values of the facilities for each control interval should be determined....

Knowledge management (KM) facilitates the capture, storage, and dissemination of knowledge using information technology. In this paper, we propose a FKM (Fuzzy Knowledge Management) approach to managing fuzzy knowledge through knowledge engineering and fuzzy logic. First, fuzziness is introduced into CGs (Conceptual Graphs) for constructing fuzzy knowledge models. Fuzzy knowledge models are use...

One of the basic principles of knowledge representation is that it is a language by which people say things about the world. Visual depictions appear particularly useful for representation of knowledge, e.g., Peirce's Existential Graphs, and Sowa’s Conceptual Graphs (CGs). Recently, a new flow-based model for representing knowledge, called the Flowthing Model (FM), has been proposed and used in...

This article extends the findings from the Resources for Enhancing Alzheimer's Caregiver Health (REACH II) program, a multisite randomized clinical trial of a multicomponent psychosocial intervention, to improve the well-being of informal caregivers (CGs) of persons with dementia. We used residual change scores and stepwise hierarchical regression analyses to explore separately in 3 racial ethn...