Iron in serum and urine specimens containing deferoxamine (a chelator used in treating acute iron intoxication) can be measured by the DuPont aca discrete-analyzer method for iron if 0.5 mL of a 100 mL/L solution of thioglycolic acid (mercaptoacetic acid) is added to the IRN-1 and IRN-2 test packs before their use. This reagent releases the unreactive chelated iron, allowing reliable colorimetr...

The Huynh electronic parameter (HEP) is a modern alternative method to determine ligand donor strengths by 13C NMR spectroscopy of metal NHC complexes containing the interest. Using HEP, properties numerous classical Werner-type and organometallic ligands have been evaluated thus far. Moreover, it has extended HEP2, which provides means measure bidentate chelators. This Highlight Review covers ...

background: iron chelators are an important part of management of patients with thalassemia. it is prudent to compare efficacy of different iron chelators in treatment of iron overload in these patients who receive regular blood transfusion. we aimed to compare the efficacy and safety of available oral iron chelator; deferasirox (exjade®) with deferasirox (osveral®) in reducing iron overload in...