Background & Aim: Identification, characterization and detection of medicinal plants chemical composition are very important for phytochemical scientific source. Sumac is one of the medicinal plants in the world that uses for industrial and pharmacological application. In this study, chemical composition of Rhus coriaria has been investigated. Experimental:</s...

Chemical probes are essential tools for understanding biological systems and for target validation, yet selecting probes for biomedical research is rarely based on objective assessment of all potential compounds. Here, we describe the Probe Miner: Chemical Probes Objective Assessment resource, capitalizing on the plethora of public medicinal chemistry data to empower quantitative, objective, da...

A goal of the Tox21 program is to transit toxicity testing from traditional in vivo models to in vitro assays that assess how chemicals affect cellular responses and toxicity pathways. A critical contribution of the NIH Chemical Genomics center (NCGC) to the Tox21 program is the implementation of a quantitative high throughput screening (qHTS) approach, using cell- and biochemical-based assays ...