www.turner-white.com G onorrhea and chlamydia are the 2 most commonly reported bacterial sexually transmitted diseases (STDs) in the United States.1 Early diagnosis is an important challenge with both gonorrhea and chlamydia because most patients do not exhibit symptoms. Neisseria gonorrhoeae can infect mucosal surfaces, including the urethra, endocervix, pharynx, and rectum. Disseminated gonoc...

Background. Pelvic inflammatory disease (PID) rarely results in diffuse ascites. Severe adhesive disease secondary to PID may lead to the formation of inclusion cysts and even pelvic peritoneal nodularity due to postinflammatory scarring and cause an elevation of serum CA-125 levels. The constellation of these findings may mimic an ovarian neoplasm. Case. We report a case of a 22-year-old femal...

Chlamydia trachomatis is currently, the major cause of bacterial sexually transmitted infections (STIs) worldwide. Infection prevalence peaks in women younger than 25 years. There is increasingly more evidence that infection with Chlamydia trachomatis can cause adverse pregnancy and infant health outcomes (stillbirth, premature rupture of membranes, puerperal infections, miscarriage, ectopic pr...

The humoral immune response to Chlamydia outer membrane protein 2 (Omp2) was studied. Omp2 is a highly genus-conserved structural protein of all Chlamydia species, containing a variable N-terminal fragment. To analyze where the immunogenic parts were localized, seven highly purified truncated fusion proteins constituting different regions of the protein were produced (Chlamydia pneumoniae-Omp2a...

Chlamydiae are obligate intracellular bacterial pathogens that exhibit a broad range of host tropism. Differences in host tropism between Chlamydia species have been linked to host variations in IFN-gamma-mediated immune responses. In mouse cells, IFN-gamma can effectively restrict growth of the human pathogen Chlamydia trachomatis but fails to control growth of the closely related mouse pathog...

BACKGROUND/OBJECTIVES Few studies of Chlamydia trachomatis incidence, especially among men, and most studies of C. trachomatis in US military populations are cross sectional prevalence surveys. A population based retrospective cohort was used to determine risk factors for repeat diagnoses of genital C. trachomatis infections among male and female soldiers with previous C. trachomatis infections...

The clinical features and aetiology of 100 consecutive symptomatic heterosexual male patients with urethritis were studied from March 1994 to August 1994 in the Genito-Urinary Medicine (GUM) Clinic, Kuala Lumpur Hospital. Gonococcal urethritis (GU) was found to be more common (53%) than non-gonococcal urethritis(47%). All patients with GU confirmed microbiologically had clinically evident ureth...

OBJECTIVE The aim of this study was to determine the prevalence of cervical Chlamydia trachomatis infection by polymerase chain reaction (PCR) in urban women undergoing routine cervical cytological screening and to investigate the relationship with age, cytology, smoking status and concurrent human papillomavirus (HPV) infection. METHODS A total of 996 women (age range 16-69 years) attending ...

AIM This study investigated the cumulative incidence of Chlamydia trachomatis infection in women treated in gynaecology departments of healthcare facilities in two towns in Serbia and one town in the Former Yugoslav Republic (FYR) of Macedonia, including their medical records in public health reports. METHODS A cross-sectional observational research design with retrospective data collection d...

The innate immune system is a critical component of host defence against microbial pathogens, but effective responses require an ability to distinguish between infectious and non-infectious insult to prevent inappropriate inflammation. Using the important obligate intracellular human pathogen Chlamydia trachomatis; an organism that causes significant immunopathology, we sought to determine crit...