Chemicals identified as endocrine-disrupting compounds (EDCs) have widespread consumer uses, yet little is known about indoor exposure. We sampled indoor air and dust in 120 homes, analyzing for 89 organic chemicals identified as EDCs. Fifty-two compounds were detected in air and 66 were detected in dust. These are the first reported measures in residential environments for over 30 of the compo...

Microlayer water, mixed layer water, epipellic and benthic sediments were collected from Tarkwa Bay end of Lagos Lagoon to analyse for chlorinated pesticide residues. Sampling was conducted between December 2008 and September 2009 during the dry and wet seasons to study effects of seasonal variation on the samples. Water samples were subjected to liquid-liquid extraction using dichloromethane w...

Organochlorine contaminants (OCs) were determined in liver and fat of seven species of seabirds (Alle alle, Uria lomvia, Cepphus grylle, Rissa tridactyla, Pagophila eburnea, Larus hyperboreus, and Fulmaris glacialis) collected in May/June 1998 from the Northwater Polynya in northern Baffin Bay. OC concentrations ranged over an order of magnitude between seabird species and OC groups, with PCBs ...

This seventy-ninth volume of IARC Monographs contains evaluations of the carcinogenic risk to humans of 19 chemicals that have produced thyroid tumours in rodents. Unless otherwise stated, the term ‘thyroid tumour’, as used in this volume, refers to neoplasms of thyroid follicular cell origin. These substances have diverse uses. A number are used as drugs, including socalled ‘anti-thyroid’ agen...

Organochlorine exposure was linked to non-Hodgkin lymphoma (NHL) risk. To determine whether this relation is modified by immune gene variation, we genotyped 61 polymorphisms in 36 immune genes in 1172 NHL cases and 982 controls from the National Cancer Institute-Surveillance, Epidemiology, and End Results (NCI-SEER) study. We examined 3 exposures with elevated risk in this study: PCB180 (plasma...

Organochlorine chemicals and polychlorinated biphenyls (PCBs) have been suspected as possible risk factors for non-Hodgkin lymphoma (NHL). We investigated PCBs and organochlorine pesticides and risk of NHL in a population-based case-control study in British Columbia, Canada. Congeners of PCBs (including dioxinlike congeners) and pesticides or pesticide metabolites were measured in plasma of 422...

Subterranean termite control accounted for 50% of the total business turnover of the Malaysian pest control industry in 2000, of which USS8-10 million were spent. About 70% of termite treatments were done on residential premises, 20% on industrial buildings and 10% on commercial buildings. The most important species are Coptotermes travians, C. curvignathus, C. havilandi C. kalshoveniand C. sep...

Concentrations of persistent organochlorines (OCs), such as DDTs, hexachlorocyclohexanes (HCHs), hexachlorobenzene (HCB), polychlorinated biphenyls (PCBs), and chlordane compounds (CHLs) were determined in 34 human adipose tissues collected from Guizhou Province, southern China, during 2002. DDT was the predominant contaminant among OCs analyzed; concentrations ranged from 420 to 20 000 ng/g on...

The United States (U.S.) National Park Service has initiated research on the atmospheric deposition and fate of semi-volatile organic compounds in its alpine, sub-Arctic, and Arctic ecosystems in the Western U.S. Results for the analysis of pesticides in seasonal snowpack samples collected in spring 2003 from seven national parks are presented herein. From a target analyte list of 47 pesticides...

During the past decades, many epidemiological, toxicological and biological studies have been performed to assess the role of environmental chemicals as potential toxicants for diverse human disorders. However, the relationships between diseases based on chemical exposure have been rarely studied by computational biology. We developed a human environmental disease network (EDN) to explore and s...