Chromosomal anomalies in human embryos produced by in vitro fertilization are very common, which include numerical (aneuploidy) and structural (deletion, duplication or others) anomalies. Our previous study indicated that chromosomal deletion(s) is the most common structural anomaly accounting for approximately 8% of euploid blastocysts. It is still unknown if these deletions in human euploid b...

Early detection of abnormalities in early pregnancy and they can be terminated once the baby was born with a disability that economic, social and cultural rights, there are a lot of families and community and overhead families and community prevent, so far none of the known human chromosomal abnormalities are treatable and the only way to deal with these diseases limit to prenatal diagnosis and...

Congenital diaphragmatic hernia (CDH) is often associated with major anomalies and chromosomal abnormalities. Chromosomal abnormalities are usually detected in 9.5% to 34% of fetuses with CDH prenatally diagnosed and the defect has also been reported in association with multiple syndromes such as Pallister-Killian syndrome, Fryns syndrome, Di George syndrome and Apert syndrome. Among the chromo...

Structural chromosomal aberrations, in the form of breaks, were found in a significantly higher proportion of bone marrow cells in patients with infective hepatitis than in controls. These anomalies were observed during the first and third weeks after the onset of jaundice but had subsided by the sixth week. Chromosomal aberrations did not appear to be related to the severity of infective hepat...

OBJECTIVES To investigate socioeconomic inequalities in outcome of pregnancy and neonatal mortality associated with congenital anomalies. DESIGN Retrospective population based registry study. SETTING East Midlands and South Yorkshire regions of England (representing about 10% of births in England and Wales). PARTICIPANTS All registered cases of nine selected congenital anomalies with poor...

Early developmental stages are particularly susceptible to disruption because this is the period for organogenesis. This refers to the 4th to 8th weeks of development. The aim of this study was to determine the pattern of congenital anomalies presenting in tertiary health facilities in Jos and any association between the anomalies. A retrospective study of 200 cases of congenital anomalies that...

In this work, the cytotoxic and genotoxic influences of oxyfluorfen herbicide were surveyed by examining mitotic index, stages, chromosomal anomalies, micronucleus percentage, comet assay parameters on somatic cells Allium cepa. The roots treated with 0.2, 0.4, 0.8 1.6 ppm concentrations 12, 24 36 h. application periods. Mitotic index was noticeably diminished in each group when matched their c...

Aim. The prognosis of the reproductive function women with pregnancy loss is complex and partly based on results karyotyping material loss. According to literature, during conception are formed same number male female fetuses, but more boys born. purpose this study was evaluate gender ratio incidence chromosomal anomalies in products (POC). Methods. Banding cytogenetic interphase mFISH centrome...

Background: With a high sensitivity and specificity, non-invasive prenatal testing (NIPT) is an incomparable screening test for fetal aneuploidy. However, the method rather newly introduced, experiences with false positive results are few. Even rare cases of discordant may cause psychological stress.
 Aim Study: The aim this study was to examine NIPT tests in high-risk pregnancies. literat...