نتایج جستجو برای: chromosomal sensitivity

تعداد نتایج: 380653  

Journal: :Methods in molecular biology 2008
Suzanne E Peterson Jurjen W Westra Christine M Paczkowski Jerold Chun

Neural stem and progenitor cells (referred to here as NSCs), located in the proliferative zones of embryonic brains, can be seen undergoing mitosis at the ventricular surface. Mitotic NSCs can be arrested in metaphase and chromosome "spreads" produced to reveal their chromosomal complement. Studies in mice and humans have revealed a prominent developmental presence of aneuploid NSCs, whereas ot...

2004
Marjan M. Weiss Ernst J. Kuipers Cindy Postma Antoine M. Snijders Daniel Pinkel Stefan G. M. Meuwissen Donna Albertson Gerrit A. Meijer

BACKGROUND & AIMS Pathogenesis of gastric cancer is driven by an accumulation of genetic changes that to a large extent occur at the chromosomal level. In order to investigate the patterns of chromosomal aberrations in gastric carcinomas, we performed genome-wide microarray based comparative genomic hybridisation (microarray CGH). With this recently developed technique chromosomal aberrations c...

فاتحی, داریوش,

Due to importance of combination therapies in cancer treatment, this study was performed to find the effects of hyperthermia and neutron irradiation and heir combination on the human lymphocytes. Blood samples were treated separately with 41.5 °C for 30 and 60 minutes, 43 °C for 15 and 30 minutes, as well as 10 cGy neutron irradiation. They also treated with hyperthermia followed by irradiation...

Journal: :Evolution 1995

Journal: :caspian journal of environmental sciences 2011
m. pourkazemi a. khosravanizadeh m.r. nowruz fashkhami

the chromosomal spread and karyotype of bleak (alburnus alburnus) from anzali lagoon were identified using tissue squashing techniques with injection of 0.5ml/100g body weight of 0.01% colchicines solution in fish fingerlings. kidney and gill tissues were then extracted and chopped in kcl 0.045m for 20 min and fixed in carnoy solution in 3 stages. the chromosomal spreads were stained in 20% gim...

Journal: :Cancer research 1999
J E Cleaver V Afzal L Feeney M McDowell W Sadinski J P Volpe D B Busch D M Coleman D W Ziffer Y Yu H Nagasawa J B Little

The xeroderma pigmentosum (XP) variant (XPV) is a form of XP that has normal excision repair but shows defective DNA replication after UV irradiation. In developing various transformed fibroblast cell lines from these patients, we have found that there are significant phenotypic changes in transformed cells that seem to correlate with inactivation of p53. After transformation with SV40, XPV cel...

Journal: :cell journal 0

introduction: the types and incidence of the chromosomal abnormalities in failed fertilized oocytes that were taken after routine in vitro fertilization (ivf) and intracytoplasmic sperm injection (icsi) programs were investingated in patients referred the royan institute. materials and method: in this study, 364 air-dried preparation of failed fertilized oocytes after either ivf (91 samples) or...

Introduction: Not being to get pregnant, after one year of unprotected sex is called infertility. In the post, infertility was mainly a female problem, but the role of male factors in infertility has denotation, although a greater percentage of this infertility is related to the deficiencies of semen. Methods: This case-control study was performed on sperm samples from 30 infertile oligoterato...

Introduction: Exposure to ionizing radiation as a result of diagnostic, treatment and occupational reasons, has created a remarkable range of cytogenetic damage in the DNA, as the first and main goal of ionizing radiation. The aim of this study is to assess the chromosomal damage in medical radiotherapy workers and its association with effective parameters such as age, sex, duration of employme...

Journal: :Journal of Cell Biology 2002

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