BACKGROUND The GOLD classification of COPD severity introduces a stage 0 (at risk) comprising individuals with productive cough and normal lung function. The aims of this study were to investigate total mortality risks in GOLD stages 0-4 with special focus on stage 0, and furthermore to assess the influence of symptoms of chronic bronchitis on mortality risks in GOLD stages 1-4. METHOD Betwee...

BACKGROUND The purpose of this cross-sectional study was to estimate the number of individuals with chronic bronchitis and/or chronic obstructive pulmonary disease in Isfahan. Our study results were compared with those of previous studies in Iran and similar studies in other countries. MATERIALS AND METHODS As a part of a population-based, cross-sectional study, 2,200 randomly selected indivi...

ventilation: a randomised placebo-controlled trial. Lancet 2001;358:2020–5. 8. Wilson R, Jones P, Schaberg T, et al. Antibiotic treatment and factors influencing short and long term outcomes of acute exacerbations of chronic bronchitis. Thorax 2006;61:337–42. 9. Patel IS, Seemungal TA, Wilks M, et al. Relationship between bacterial colonization and the frequency, character and severity of COPD ...

"'THE syndrome has its philosophical basis not in specific disease factors but in a chain of physiological processes, interference of which at any point produces the same impairment of bodily function. The same syndrome may thus arise from many different causes. This newer view inspires a far more catholic concept of xetiology and renders pointless many existing controversies." SIR HAROLD HIMSW...

This study was initiated with the question: Do defects in neutrophil functions predispose patients with chronic bronchitis to their recurrent bacterial infections? Forty five patients with chronic bronchitis and recurrent bacterial infections were studied. A number of aspects of neutrophil functions reflecting migratory and phagocytic functions and oxidative metabolism were measured in vitro, o...

OBJECTIVES The possibility that a bronchial inflammatory process could be involved with a chronic nonproductive cough without other potential causes such as postnasal drip syndrome, bronchial asthma, gastroesophageal reflux, chronic bronchitis, bronchiectasis, or the use of angiotensin-converting enzyme inhibitors has not been clearly described. We investigated the possibility that a chronic no...