Most oral involvement in the mucocutaneous diseases is related mainly to disorders with a prominent immunological component, especially lichen planus and pemphigoid. However, less common conditions such as pemphigus, dermatitis herpetiformis, linear IgA disease, erythema multiforme, chronic ulcerative stomatitis and other conditions may need to be excluded. Diagnosis is initially clinical, base...

Lichen planus (LP) is a chronic autoimmune mucocutaneous disease that predominantly affects adults and occurs less frequently in the pediatric patients. Oral LP in childhood is a rare entity with very few cases cited in the literature. The objective of this paper is to contribute a clinically and histologically documented case of juvenile oral LP to the literature. Despite the fact of rare occu...

abstract background immune thrombocytopenic purpura (itp) is the most prevalent cause of thrombocytopenia in children. despite the importance of itp in children under 2- years old, only a few publications are available in the literature. itp usually presents itself as   isolated thrombocytopenia and mucocutaneous bleeding. materials and methods this study was conducted on 187 under 2- year-old ...

Pemphigus vulgaris is a serious chronic mucocutaneous ailment. In recent decades advances in diagnostic and therapeutic measures have led to a significant decline in morbidity and mortality. However, with the advent of active and prolonged immunotherapy involving corticosteroids, there has been a rise in steroid-associated complications. This has led to significant concern globally over the sen...

introduction kawasaki disease (kd) is an acute systemic vasculitis, of unknown etiology, that mainly affects infants and young children. although originally thought to be a benign illness, kd may prove fatal, especially if the diagnosis is delayed due to a nonclassic presentation. case presentation here, we present the case of a 4-year-old girl with a history of prolonged fever. her physical ex...

BACKGROUND AND AIMS Human immunodeficiency virus (HIV) is associated with various mucocutaneous features, which may be the first pointer towards the existence of HIV infection. This study was done to note the different mucocutaneous lesions present in the HIV population in eastern India. METHODS Four hundred and ten HIV seropositive patients attending the outpatient and inpatient departments ...

OBJECTIVES To investigate the significance of cytomegalovirus (CMV) in mucocutaneous lesions in patients with human immunodeficiency virus (HIV), and to elucidate its pathogenetic role in lesions genesis. DESIGN Retrospective (study 1) and prospective (studies 2 and 3) surveys. SETTING Departments of Dermatology, Pathology, and Microbiology at a university hospital in Madrid, Spain. PATIE...

Oregano essential oil (OEO) possesses antimicrobial, antioxidant, and preservative properties, making it a promising candidate for various biotechnological biomedical applications. However, the inherent volatility, hydrophobicity, susceptibility to external factors such as light, heat, oxygen can compromise its stability bioactivity. To overcome these limitations, silver nanoparticles (AgNPs) w...

BACKGROUND Behcet's disease (BD) is a chronic relapsing multisystem inflammatory disorder with mucocutaneous, ocular, articular, vascular, gastrointestinal and central nervous system manifestations. Tumor necrosis factor (TNF)-alpha is believed to play a pivotal role in BD. Therapeutic blockade of the activity of TNF has been successfully given in a short course of therapy with favorable effect...