Chronic obstructive pulmonary disease (COPD) is a common chronic airway inflammatory disease. With its heterogeneity in clinical manifestations, treatment responses and prognosis, biomarkers that can predict benefits risk stratification of deterioration are very important. In recent years, many studies have reported eosinophils highly involved the development inflammation COPD. The baseline blo...

The presence of chronic bronchitis predicts a more rapid decline of forced expiratory volume in one second (FEV(1)) in patients with chronic obstructive pulmonary disease (COPD). The hallmark of COPD is airway inflammation. It was hypothesised that COPD patients with chronic bronchitis are characterised by a distinct inflammatory cell profile, as measured in bronchial biopsies and sputum. From ...

The authors performed bronchoscopic examination using an ultrathin bronchoscope to determine the characteristics of the peripheral airways in chronic obstructive pulmonary disease (COPD). The study population comprised 13 healthy control subjects, 10 patients with chronic bronchitis without airflow limitation, and 20 patients with COPD. The COPD patients were divided clinically into 10 with chr...

phosphodiesterase-4 inhibitor BAY 19-8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD). Pulm Pharmacol Ther 2003; 16: 341–347. 5 Hatzelmann A, Morcillo EJ, Lungarella G, et al. The preclinical pharmacology of roflumilast – a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease. Pulm Pharmaco...

Novel therapies in chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) continues to be a major medical problem. With no curative therapy being available, management of severe exacerbations of COPD should be directed at relieving symptoms and restoring functional capacity [1]. Mortality from COPD continues to rise and the World Health Organisation predicts it will ...

This study assessed the feasibility of pulmonary telerehabilitation’s (PTR) acceptability, implementation, practicality, and adaptation for people with Chronic Obstructive Pulmonary Disease (COPD) in Brazil. It also explored associations clinical socioeconomic features Brazilians COPD. mixed-method included thirty-one participants COPD (age 62±10 years; FEV1= 72±14% predicted). Most (74.2%) rep...

Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a lung disease characterized by chronic obstruction of airflow that interferes with normal breathing and not fully reversible. COPD progressive airway associated psychological distress Screening the psychiatric disorders in patients will be helpful better management assuring compliance as well help to improve quality life these leadi...

Care Med 2001;164:1008–11. 8 Kanazawa H, Hirata K, Yoshikawa J. Accelerated decline of lung function in COPD patients with chronic hepatitis C virus infection: a preliminary study based on small numbers of patients. Chest 2003;123:596–9. 9 Schols AM, Slangen J, Volovics L, et al. Weight loss is a reversible factor in the prognosis of chronic obstructive pulmonary disease. Am J Respir Crit Care ...

In chronic obstructive pulmonary disease(COPD) patients use extensively supplementary respiratory muscles such as trapezium and scalenes in order to facilitate ventilation. These situations cause pain restricting by the upper body mobility neck movements. This study was conducted investigate presence of individuals with COPD compare it healthy individuals. The included sixty-two COPD(COPD group...