Chronic inactivity may not be the sole factor involved in the myopathy of chronic obstructive pulmonary disease (COPD) patients. One hypothesis is that exercise-induced oxidative stress that leads to muscle alterations may also be involved. This study investigated whether exercise localised to a peripheral muscle group would induce oxidative stress in COPD patients. Eleven COPD patients (FEV1 1...

Adams, S. G., Smith, P. K., Allan, P. F., Anzueto, A., Pugh, J. A., & Cornell, J. E. (2007). Systematic review of the chronic care model in chronic obstructive pulmonary disease prevention and management. Archives of Internal Medicine, 167(6), 551-551-561. While implementation of the chronic care model (CCM) has been shown to be an effective preventative strategy to improve outcomes in diabetes...

OBJECTIVES/HYPOTHESIS Although chronic obstructive pulmonary disease (COPD) is a common comorbidity in patients undergoing laryngeal cancer surgery, the impact of this comorbidity in this setting is not well established. In this analysis, we used the Nationwide Inpatient Sample (NIS) to elucidate the impact of COPD on outcomes after laryngectomy for laryngeal cancer. METHODS The NIS was queri...

In many countries, the protease inhibitor (SERPINA1) PI*S allele is more common than PI*Z, the allele responsible for most cases of chronic obstructive pulmonary disease (COPD) due to severe alpha 1-antitrypsin deficiency. However, the risk of COPD due to the PI*S allele is not clear. The current authors located studies that addressed the risk of COPD or measured lung function in individuals wi...

1 The British Thoracic Society. Intermediate care – hospital-athome in chronic obstructive pulmonary disease. British Thoracic Society guidelines. Thorax 2007; 62: 200–210. 2 British Lung Foundation. Invisible lives – Chronic Obstructive Pulmonary Disease (COPD) – finding the missing millions. www.lunguk.org Date last updated: November 2007. Date last accessed: April 2008. 3 Global Initiative f...

Assessment techniques and treatment strategies, such as medical management, oxygen management, chest physical therapy, and pulmonary rehabilitation, for patients with chronic obstructive pulmonary disease (COPD) are discussed. Clinically appropriate, evidence-based rehabilitation programs for home care may help to reduce care costs, reduce the impact of this chronic disease on patients with COP...

Patients with chronic obstructive pulmonary disease (COPD) show impaired hypoxic pulmonary vasoconstriction that might contribute to abnormal gas exchange and could be related to endothelial dysfunction in pulmonary arteries. The aim of the study was to investigate the response of PA to hypoxic stimulus in vitro in COPD, and the role of endothelium-derived nitric oxide (NO) in this response. Th...

Chronic obstructive pulmonary disease (COPD) is a debilitating pulmonary disorder with systemic effects, and it is the fourth leading cause of death in the United States. COPD patients not only develop respiratory limitations, but can also demonstrate systemic wasting, features of depression, and can succumb to social isolation. Smoking cessation is crucial, and pharmacotherapy with bronchodila...

The aim of this study was to quantify the global prevalence of chronic obstructive pulmonary disease (COPD) by means of a systematic review and random effects meta-analysis. PubMed was searched for population-based prevalence estimates published during the period 1990-2004. Articles were included if they: 1) provided total population or sex-specific estimates for COPD, chronic bronchitis and/or...

background: chronic obstructive pulmonary disease (copd) is a major health dilemma and cause of morbidity and mortality in either industrialized or developing countries and inhaled corticosteroids are widely used worldwide in these patients. in this systematic review, we aimed to analyze the effectiveness of these gents compared to placebo. methods: pubmed and google scholar literature search h...