AIM To critically appraise recent research into associations between periodontal disease and systemic diseases and conditions specifically respiratory disease, chronic kidney disease, rheumatoid arthritis, cognitive impairment, obesity, metabolic syndrome and cancer. METHODS A MEDLINE literature search of papers published between 2002 and April 2012 was conducted. Studies that included period...

OBJECTIVE To study the extent of periodontal disease in diabetic and non-diabetic periodontitis patients, and to investigate the relationship of dyslipidemia and periodontal disease, in diabetic and non-diabetic periodontitis patients. METHODS This is a cross-sectional study at the Department of Preventive Dental Sciences (College of Dentistry) and Department of Physiology (College of Medicin...

Although a number of inflammatory cytokines have been shown to be associated with periodontal pathogenesis, it is important to investigate further whether these biomarkers are associated with the degree of success in nonsurgical treatment of chronic periodontitis. The aim of the present study was to quantify the total levels of interleukin (IL)-1α, -1β, -6, -10 and tumour necrosis factor (TNF)-...

Periodontitis is one of the most prevalent human inflammatory diseases. The major clinical phenotypes of this polymicrobial, biofilm-mediated disease are chronic and aggressive periodontitis, the latter being characterized by a rapid course of destruction that is generally attributed to an altered immune-inflammatory response against periodontal pathogens. Still, the biological basis for the pa...

Background: Chronic apical periodontitis is potential infection with poor symptoms that are easily overlooked. Disease progession can lead to cellulitis, osteomyelitis, sinusitis, endocarditis, nephritis, arthritis, persistent fever and sepsis. In recent times, thanks advances in endodontic improving instruments, root canal antiseptics, techniques for shaping, obturation canals, treatment has a...

BACKGROUND Levels of pro-inflammatory cytokine (IL-1β) released by peripheral blood leukocyte medium (PBLM), isolated from chronic periodontitis patients (P) before therapy and matched to controls, were determined in the presence or absence of non-opsonized Escherichia coli and Staphylococcus aureus. MATERIAL AND METHODS In this investigation, 26 patients with untreated, severe, generalized, ch...

PURPOSE The purpose of the present study was to perform a pattern analysis in patients with temporomandibular disorder (TMD) resulting from unilateral mastication due to chronic periodontitis. METHODS Thirty participants with signs or symptoms of TMD who engaged in unilateral mastication due to periodontitis-related discomfort (test group) were selected. Another 30 subjects exhibiting signs o...

COPD is recognized as having a series of comorbidities potentially related to common inflammatory processes. Periodontitis is one of the most common human inflammatory diseases and has previously been associated with COPD in numerous observational studies. As periodontitis and COPD are both chronic, progressive conditions characterized by neutrophilic inflammation with subsequent proteolytic de...

Objectives: Periodontal pathogens need acidic environments to proliferate in periodontium, and their growth is affected by the salivary flow rate and pH of the mouth. Alterations in flow and acidity of saliva have an important effect on oral diseases such as periodontitis. This study was designed to compare salivary pH and flow rate before and after using green tea, black tea and coffee in pati...

background: despite the outbreak in dental science, oral and dental complications in alzheimer are of the unsolved problems. it is assumed that tumor necrosis factor-α, which is a key factor in alzheimer, has a relation with periodontal complications in patients with alzheimer disease. the present study evaluated the effect of chronic periodontitis on serum levels of tumor necrosis factor-α in ...