نتایج جستجو برای: circumsporozoite protein

تعداد نتایج: 1234774  

Journal: :Annual review of cell and developmental biology 2004
Stefan H I Kappe Carlos A Buscaglia Victor Nussenzweig

Plasmodium sporozoites display complex phenotypes including gliding motility and invasion of and transmigration through cells in the mosquito vector and the vertebrate host. Sporozoite studies have been difficult to perform because of technical concerns. Nevertheless, they have already provided insights into several aspects of sporozoite biology, shared in part with other apicomplexan invasive ...

Journal: :The Southeast Asian journal of tropical medicine and public health 2004
Chutima Kumkhaek Kooruethai Phra-ek Pratap Singhasivanon Sornchai Looareesuwan Chakrit Hirunpetcharat Alan Brockman Anne Charlotte Grüner Nicolas Lebrun Laurent Rénia François Nosten Georges Snounou Srisin Khusmith

Allelic variation in the Plasmodium falciparum circumsporozoite protein (CS) gene has been determined by sequencing the immunodominant T-cell epitopes, Th2R and Th3R, from 95 isolates from two malaria-endemic areas in the west of Thailand. Comparison with a reference sequence revealed only non-synonymous point mutations in the two epitope regions. Point mutations were found outside these epitop...

2011
Peter Van den Eede Veronica E. Soto-Calle Christopher Delgado Dionicia Gamboa Tanilu Grande Hugo Rodriguez Alejandro Llanos-Cuentas Jozef Anné Umberto D'Alessandro Annette Erhart

BACKGROUND There is an increasing body of literature reporting treatment failure of the currently recommended radical treatment of Plasmodium vivax infections. As P. vivax is the main malaria species outside the African continent, emerging tolerance to its radical treatment regime could have major consequences in countries like Peru, where 80% of malaria cases are due to P. vivax. Here we descr...

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