BACKGROUND AND PURPOSE Acinetobacter baumannii isolates containing class 1 integrons belong to different clones, but only a few strains are successful at causing infection. This study was conducted to compare the characteristics among these clones with different epidemicity. METHODS Eighty eight bacteremic isolates of A. baumannii were collected in a medical center in Taiwan during a 3-year p...

In 200 sulfonamide-resistant Portuguese Salmonella isolates, 152 sul1, 74 sul2, and 14 sul3 genes were detected. Class 1 integrons were always associated with sul genes, including sul3 alone in some isolates. The sul3 gene has been identified in isolates from different sources and serotypes, which also carried a class 1 integron with aadA and dfrA gene cassettes.

Sir, IMP enzymes are one of the class B-type metallo-b-lactamases found in Acinetobacter baumannii. So far, nine IMP enzymes have been reported in this species, many as isolated cases (GenBank accession numbers DQ845788 and AB184977). IMP b-lactamases are often present in class 1 integrons, which, in turn, are embedded in transposons, resulting in highly transmissible genetic units. The majorit...

Sir, CTX-M enzymes include more than 60 variants belonging to five different clusters (CTX-M-1, CTX-M-2, CTX-M-8, CTX-M-9 and CTX-M-25) according to their amino acid sequence. In recent years, CTX-M enzymes have become the most prevalent extended-spectrum b-lactamases (ESBLs), both in nosocomial and in community settings. Different genetic elements might be involved in the mobilization of blaCT...

s: The aadA genes, encoding resistance to streptomycin and spectinomycin, have been found as gene cassettes in different gram-negative and gram-positive bacterial species. The present report has revealed that the sequence of a new gene, aadA5, combining with the trimethoprim resistance gene dfr17 occured in a class 1integron. The integron was identified in a nosocomial pathogen Enterobacter clo...

BACKGROUND The global incidence of foodborne infections and antibiotic resistance is recently increased and considered of public health concern. Currently, scarcely information is available on foodborne infections and ESBL associated with poultry and beef meat in Egypt. METHODS In total, 180 chicken and beef meat samples as well as internal organs were collected from different districts in no...

Plasmid-located extended-spectrum-lactamase (ESBL) genes are mostly found in Enterobacteriaceae (6). A new class A ESBL was identified in Klebsiella pneumoniae. It was named GES-1, and it corresponds to the ceftazidime-hydrolyzing enzyme (8). GES-type ESBLs have emerged in a variety of countries, and there are 18 known variants (http://www.lahey.org/Studies/). In the present study, we investiga...