There is a large discrepancy between the findings of observational and experimental studies on the effects of post-menopausal hormone therapy (HT) and coronary heart disease risk. Observational studies, mainly comprising peri-menopausal women, report risk reductions up to 30-50%, whereas the experimental studies, comprising elderly women, do not show coronary protection. Suggested explanations ...

Maceration at liquid nitrogen temperatures, use of poly-vinylpyrrolidone, and careful pH control are essential to the isolation of ribosomes and polysomes from deciduous fruit tissue. Characteristics of the ribosomes and constituent RNA are described. The distribution of ribosomes among monomer and polymer forms remains relatively constant until fruit reach the climacteric peak, after which the...

Abstract Menopausal transition (premenopause) is the phase in ageing process of women representing from reproductive stage life to non-reproductive stage. With improvements average expectancy, live an increased proportion their lives postmenopause. The consequences oestrogen loss are early symptoms (psychological and vasomotor), genitourinary syndrome (intermediate), as well postmenopausal oste...

BACKGROUND tibolone at usual doses of 2.5 mg/day in postmenopausal women has been shown to improve climacteric complaints, without affecting endometrial thickness and lipid profile or blood glucose. However, the potentially similar efficacy, but better tolerability, of a low dose of this drug (1.25 mg) has never been established. METHODS 162 healthy, non-obese, post-menopausal women, aged 40-...

numbers will increase to 60 million in the next 10 years and the attitudes about menopause are continuing to move from being viewed as a clinical syndrome to a natural transition have opened the way for more natural and comprehensive management of menopausal symptoms. This review will discuss the physiological and clinical aspects of menopause, with a view to both the inevitable and preventable...