BACKGROUND Prevalence of paediatric voice disorders has been reported as 6-9% in children of school age. The appropriate diagnosis and management of paediatric voice disorders is essential for progress in education and psychosocial development. This paper presents a review of a UK tertiary paediatric voice clinic experience of referral patterns, diagnosis, management and socioeconomic variation...

Tumor lysis syndrome (TLS) is a group of metabolic abnormalities that are usually seen in cancer patients treated with chemotherapy although it can occasionally occur spontaneously without chemotherapy in patients with a high tumor burden. It is due to the rapid lysis of tumor cells resulting in the release of large amounts of intracellular contents in the blood stream. This results in the rapi...

MICHEL FOUCAULT'S Naissance de la clinique (Paris, Presses Universitaires de France, 1963) makes a brilliant case for the sudden emergence in the late eighteenth century of the hospital clinic as the central concept and institution of Western medicine. Foucault's thesis, briefly stated, sees the birth of the clinic as an "essential mutation in medical knowledge" arising out of a general epistem...