نتایج جستجو برای: clinical toxicology
تعداد نتایج: 1170768 فیلتر نتایج به سال:
Analytical data from the clinical toxicology laboratory of a large urban hospital, the Los Angeles County--University of Southern California Medical Center, are reported for the year 1976 and are compared to similar data previously documented for the year 1972. Drugs assayed, number of tests requested, and number of positive results are collated. Data on 58 assays show that the overwhelming maj...
We report one year’s analytical data from a clinical toxicology laboratory of a large urban hospital. The laboratory was designed to perform tests on seriously ill patients believed to be suffering from possible drug overdose. The data describe the types and numbers of tests requested and percent positive. Barbiturates, ethanol, a “hypnotic screen,” phenothiazines, and salicylates were the lead...
Intoxication is still the major cause of morbidity and mortality worldwide. Despite growing number global studies about intoxication, comprehensive bibliometric are not available in literature. This study aims to analyze scientific articles intoxication/poisoning evaluate this subject matter from a holistic point view. Studies intoxication that were published years between 1975 2020 downloaded ...
Evolutionary toxicology is a young field that has grown rapidly in the past two decades. The potential of this field comes from the ability to link chemical contamination to multigenerational and population-wide effects in various species. The advancements and rapidly decreasing costs of -omic tools are improving the power and resolution of evolutionary toxicology studies. In this manuscript, w...
The field of predictive toxicology requires the development of open, public, computable, standardized toxicology vocabularies and ontologies to support the applications required by in silico, in vitro, and in vivo toxicology methods and related analysis and reporting activities. In this article we review ontology developments based on a set of perspectives showing how ontologies are being used ...
Genetic toxicology is the scientific discipline dealing with the effects of chemical, physical and biological agents on the heredity of living organisms. The Internet offers a wide range of online digital resources for the field of Genetic Toxicology. The history of genetic toxicology and electronic data collections are reviewed. Web-based resources at US National Library of Medicine (NLM), inc...
The attitudes and experiences of pathologists and coroners to the provision of biochemical forensic toxicology in the Republic of Ireland were determined using separate questionnaires to each group anonymously. Replies were received from 36/88 (41%) of pathologists and 19/71 (27%) of coroners. 37% of coroners considered that histopathologists give an adequate opinion in forensic toxicology yet ...
This paper surveys recent, as yet unpublished, statistical studies arising from research in genetic toxicology within the U.S. National Toxicology Program (NTP). These studies all involve analyses of data from Ames Salmonella/microsome mutagenicity tests, but the statistical methodologies are broadly applicable. Three issues are addressed: First, what is a tenable sampling model for Ames test d...
The purpose of this paper is to present some of the more carefully studied aspects of the preclinical toxicology of antineo-plastic agents, and apply these findings (with certain obvious cautions) to the area of environmental toxicology. Most of the studies to be described here are the result of applied toxicologic studies performed in support of the clinical introduction of new chemicals in th...
Gas chromatography in combination with mass spectrometry (GC-MS) plays an important role in the field of analytical toxicology. The identification of unknown compounds is very frequently undertaken with GC-MS and utilizing mass spectral libraries. Currently available libraries for analytical toxicology were compared for overlapping and uniqueness of their entries. Furthermore, the widely known ...
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