Middle-censoring is considered as a modern general scheme of censoring. In this paper, we study the analysis of middle-censored data with Burr-XII distribution which is considered one of the most popular and flexible distributions for modeling stochastic events and lifetime for many products. The parameters are estimated by the maximum likelihood method and the Bayes estimation under gamma prio...

Analyzing events over time is often complicated by incomplete, or censored, observations. Special non-parametric statistical methods were developed to overcome difficulties in summarizing and comparing censored data. Life-table (actuarial) method and Kaplan-Meier method are described with an explanation of survival curves. For the didactic purpose authors prepared a workbook based on most widel...

In his discussion of Cox's (1972) paper on proportional hazards regression, Breslow (1972) provided the maximum likelihood estimator for the cumulative baseline hazard function. This estimator is commonly used in practice. The estimator has also been highly valuable in the further development of Cox regression and semiparametric inference with censored data. The present paper describes the Bres...

The package icenReg provides classic survival regression models for interval-censored data. We present an update to the package that extends the parametric models into the Bayesian framework. Core additions include functionality to define the regression model with the standard regression syntax while providing a custom prior function. Several other utility functions are presented that allow for...

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how to cite this article: mollamohammadi m, tonekaboni sh, pirzadeh z, vahedian m . pregabalin in childhood epilepsy: a clinical trialiran j child neurol. 2014 autumn;8(4): 62-65. abstract objective the prevalence of active epilepsy is about 0.5–1%, and approximately 70% of patients are cured with first anti-epileptic drugs and the remaining patients need multiple drugs. pregabalin as an add-on...

glycine allele at codon 16 has previously been associated with the increase in asthma severity, bronchial hyperresponsiveness and also the increase in inhaled corticosteroid dependence. this study was designed to evaluate the genetic alleles in mild asthma.thirty-four patients with diagnosis of mild asthma (fev1 ≥ 80%, positive methacholine test) and body mass index (bmi ≤ 30 kg/m2) were includ...

We consider longitudinal clinical data for HIV patients undergoing treatment interruptions. We use a nonlinear dynamical mathematical model in attempts to fit individual patient data. A statistically-based censored data method is combined with inverse problem techniques to estimate dynamic parameters. The predictive capabilities of this approach are demonstrated by comparing simulations based o...