In view of the limited information on the pharmacokinetics of oseltamivir (OSE) during pregnancy, this study aims to evaluate the placental transportation of OSE and its active metabolite oseltamivir carboxylic acid (OCA) in rats. A validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) system coupled to an in vivo transplacental model has been developed to determine OSE and OCA in...

Pellegrin A.O., Miranda K.L., Figueiredo J.F., Barbosa E.F. & Lage A.P. 2011. The use of enzyme-linked immunosorbent assay and immunoblotting for the detection of Campylobacter fetus immunoglobulins in the cervico-vaginal mucus of female cattle. Pesquisa Veterinária Brasileira 31(3):247-254. Embrapa Pantanal, Rua 21 de Setembro 1880, Corumbá, MS 79320-900, Brazil. E-mail: [email protected]...

We propose a robust method that allows a periodic or a chaotic multi-stable system to be transformed to a monostable system at an orbit with dominant frequency of any of the coexisting attractors. Our approach implies the selection of a particular attractor by periodic external modulation with frequency close to the dominant frequency in the power spectrum of a desired orbit and simultaneous an...

Objective The present study is planned to discuss the clinical value of prenatal 3D ultra-sonic diagnosis on fetus hemivertebra deformity through the retrospective analysis of clinical data of fetus hemivertebra deformity. Methods Selected 9 fetus hemivertebra deformity cases, which have been admitted to our hospital during the period from January, 2010 to January, 2016 as study samples, and ...

Placenta is a transitory organ which simultaneously separate and connect mother and fetus. It has the major importance in the nutrition of fetus, scavenger waste products from fetus, secretion of hormones and immunological factors, allowing fetus to grow in a sea of maternal immunologic environment and regulating mother metabolism. Also, placenta protects fetus to some infectious agents. It has...

We measured deoxycorticosterone (DOC) and progesterone (P) in plasma of 47 women pregnant with a dead fetus and sequentially throughout gestation in 35 women pregnant with a live fetus. When P levels in plasma were low, the plasma levels of DOC in women pregnant with a dead fetus varied but usually were similar to those in women pregnant with a live fetus. However, when P levels were high, the ...

Campylobacter fetus subsp. testudinum has been isolated from reptiles and humans. This Campylobacter subspecies is genetically distinct from other C. fetus subspecies. Here, we present the first whole-genome sequence for this C. fetus subspecies.

BACKGROUND AND OBJECTIVES Fetus prenatally diagnosed with neck tumors, or with any other disease that obstructs the airways, should not be treated conventionally, as the assistant physician has to face two challenges right after the infant's delivery: the limited time to establish the access to the potentially difficult airways and the lack of anesthesia of the neonate in case of instrumentatio...

Excess nutritional supply to the growing fetus, resulting from maternal diabetes and obesity, is associated with increased risks of fetal maldevelopment adverse metabolic conditions in postnatal life. The placenta, interposed between mother serves as gateway two circulations usually considered mediate exposures fetus through a direct line. In this Perspective, however, we argue that placenta no...